B7J161 (KCY_BORBZ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	BbuZS7_0128

Organism

Borrelia burgdorferi (strain ZS7) [Complete proteome] [HAMAP]

Taxonomic identifier

445985 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	221 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 221	221	Cytidylate kinase HAMAP MF_00238		PRO_1000119011
Regions
	Nucleotide binding	7 – 15	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	B7J161 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 3C68156A418E9F68	FASTA	221	25,572
	10 20 30 40 50 60 MIIAIDGPSA SGKSSIAREL GVRLNYKFIS SGHLYRIITL IAQRSLMNSC DFISEDSLLN 70 80 90 100 110 120 LILENDISFN NSTFLLNGEN VENQILNDKI DFQVSFYSSY VGIRNIVNKK LREVVKFSDD 130 140 150 160 170 180 NYIIEGRDIT TVVFPESEFK IYLDASVKVR ALRRYKQRNG NETLEELERT LKRRDDVDKK 190 200 210 220 KQYGKLKLSK GVFYLDTSYK GLDDVCNIII EKFNLKKVRE R

References

[1]

"Whole-genome sequences of thirteen isolates of Borrelia burgdorferi." Schutzer S.E., Fraser-Liggett C.M., Casjens S.R., Qiu W.G., Dunn J.J., Mongodin E.F., Luft B.J. J. Bacteriol. 193:1018-1020(2011) [PubMed: 20935092] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ZS7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001205 Genomic DNA. Translation: ACK74903.1.
RefSeq	YP_002374656.1. NC_011728.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B7J161.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000002737; EBBORP00000002476; EBBORG00000002737.
GeneID	7106935.
GenomeReviews	Gene locus BbuZS7_0128 in contig CP001205_GR.
KEGG	bbz:BbuZS7_0128.
PATRIC	20559695. VBIBorBur54821_0271.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000007027.
HOGENOM	HBG354377.
OMA	GIRNIVN.
ProtClustDB	CLSK507373.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_BORBZ

Accession

Primary (citable) accession number: B7J161

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	January 25, 2012
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program