B7J0L4 (GCP_BORBZ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	BbuZS7_0797

Organism

Borrelia burgdorferi (strain ZS7) [Complete proteome] [HAMAP]

Taxonomic identifier

445985 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 346	346	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_1000145948

Sequences

	Sequence		Length	Mass (Da)
	B7J0L4 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 7D12FE7D953B8380	FASTA	346	38,482
	10 20 30 40 50 60 MKVLGIETSC DDCCVAVVEN GIHILSNIKL NQPEHKKYYG IVPEIASRLH TEAIMSVCIK 70 80 90 100 110 120 ALKKANTKIS EIDLIAVTSR PGLIGSLIVG LNFAKGLAIS LKKPIICIDH ILGHLYAPLM 130 140 150 160 170 180 HSKIEYPFIS LLLSGGHTLI AKQKNFDDVE ILGRTLDDAC GEAFDKVAKH YDMGFPGGPN 190 200 210 220 230 240 IEQISKNGDE NTFQFPVTTF KKKENWYDFS YSGLKTACIH QLEKFKSKDN PTTKNNIAAS 250 260 270 280 290 300 FQKAAFENLI TPLKRAIKDT QINKLVIAGG VASNLYLREK IDKLKIQTYY PPLDLCTDNG 310 320 330 340 AMIAGLGFNM YLKYGESPIE IDANSRIENY KNQYRGKNNE KNFSNA

References

[1]

"Whole-genome sequences of thirteen isolates of Borrelia burgdorferi." Schutzer S.E., Fraser-Liggett C.M., Casjens S.R., Qiu W.G., Dunn J.J., Mongodin E.F., Luft B.J. J. Bacteriol. 193:1018-1020(2011) [PubMed: 20935092] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ZS7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001205 Genomic DNA. Translation: ACK74693.1.
RefSeq	YP_002375267.1. NC_011728.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B7J0L4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000002856; EBBORP00000002595; EBBORG00000002856.
GeneID	7106089.
GenomeReviews	Gene locus BbuZS7_0797 in contig CP001205_GR.
KEGG	bbz:BbuZS7_0797.
PATRIC	20561023. VBIBorBur54821_0902.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000006822.
HOGENOM	HBG304663.
OMA	PAVGVHH.
ProtClustDB	PRK09604.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_BORBZ

Accession

Primary (citable) accession number: B7J0L4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program