B7J0L2 (MURG_BORBZ) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 25.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase EC=2.4.1.227 Alternative name(s): Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase | ||||
| Gene names |
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| Organism | Borrelia burgdorferi (strain ZS7) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 445985 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group |
Protein attributes
| Sequence length | 363 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) By similarity. HAMAP MF_00033 |
| Catalytic activity | UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00033 |
| Pathway | Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00033 |
| Subcellular location | Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_00033. |
| Sequence similarities | Belongs to the glycosyltransferase 28 family. MurG subfamily. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 363 | 363 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase HAMAP MF_00033 | PRO_1000116469 | |||
Sequences
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References
| [1] | "Whole-genome sequences of thirteen isolates of Borrelia burgdorferi." Schutzer S.E., Fraser-Liggett C.M., Casjens S.R., Qiu W.G., Dunn J.J., Mongodin E.F., Luft B.J. J. Bacteriol. 193:1018-1020(2011) [PubMed: 20935092] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ZS7. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP001205 Genomic DNA. Translation: ACK74993.1. |
| RefSeq | YP_002375265.1. NC_011728.1. |
3D structure databases | |
| ProteinModelPortal | B7J0L2. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | B7J0L2. |
Protein family/group databases | |
| CAZy | GT28. Glycosyltransferase Family 28. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBBORT00000003133; EBBORP00000002872; EBBORG00000003133. |
| GeneID | 7106220. |
| GenomeReviews | Gene locus BbuZS7_0795 in contig CP001205_GR. |
| KEGG | bbz:BbuZS7_0795. |
| PATRIC | 20561019. VBIBorBur54821_0900. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| GeneTree | EBGT00050000007289. |
| HOGENOM | HBG617076. |
| OMA | HICGKGN. |
| ProtClustDB | PRK00726. |
Family and domain databases | |
| HAMAP | MF_00033. MurG. [Tree] |
| InterPro | IPR006009. GlcNAc_MurG. IPR004276. Glyco_trans_28. IPR007235. Glyco_trans_28_C. [Graphical view] |
| KO | K02563. |
| PANTHER | PTHR21015:SF22. PTHR21015:SF22. 1 hit. |
| Pfam | PF04101. Glyco_tran_28_C. 1 hit. PF03033. Glyco_transf_28. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01133. MurG. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | MURG_BORBZ | ||||||||
| Accession | Primary (citable) accession number: B7J0L2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with