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Reviewed, UniProtKB/Swiss-Prot B7J0L2 (MURG_BORBZ)

Last modified October 13, 2009. Version 8. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
    EC=2.4.1.227
Alternative name(s):
    Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
Gene names
Name: murG
Ordered Locus Names: BbuZS7_0795
OrganismBorrelia burgdorferi (strain ZS7) [Complete proteome] [HAMAP]
Taxonomic identifier445985 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group

Protein attributes

Sequence length363 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) By similarity.

Catalytic activity

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00033

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00033

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity.

Sequence similarities

Belongs to the glycosyltransferase 28 family. MurG subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 363363UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase HAMAP MF_00033
PRO_1000116469

Sequences

Sequence LengthMass (Da)Tools
B7J0L2-1 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 1BAFA347384DB235

FASTA36341,118
        10         20         30         40         50         60 
MSNKKIIFFT GGGTGGHVFP GISIIQKLKE FDNEIEFFWI GKKNSIEEKL IKEQDNIKFI 

        70         80         90        100        110        120 
SIPCGKLRRY FSFKNFTDFF KVILGIIKSF YVLKKYKPQL IYATGGFVST PAIIASSLLK 

       130        140        150        160        170        180 
IKSITHEMDL DPGLATKINS KFANNIHISF KESEKYFKNY KNIIYTGSPI RREFLNPDPK 

       190        200        210        220        230        240 
IIKQLTQNTN KPIISILGGS LGANALNNLA LCIKKDAEIY FIHQSGKNLN DLSEKNYLRR 

       250        260        270        280        290        300 
QFFNAEEMAS IVKFSNLIIS RAGAGAIKEF ANAGACAILI PFKKGSRGDQ IKNAKLLTNQ 

       310        320        330        340        350        360 
NACIYIDEDE ILNINILKII KKTLKDREKI NSLKENIKKF NNKHSSTLIA KLLIKDIKET 


KSK 

« Hide

References

[1]"Genome sequence of Borrelia burgdorferi strain ZS7."
Fraser-Liggett C.M., Mongodin E.F., Casjens B., Dunn J., Luft B., Qiu W., Schutzer S., Ouyang S.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP001205 Genomic DNA. Translation: ACK74993.1.
RefSeqYP_002375265.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID7106220.
GenomeReviewsGene locus BbuZS7_0795 in contig CP001205_GR.
KEGGbbz:BbuZS7_0795.

Organism-specific databases

CMRSearch...

Family and domain databases

HAMAPMF_00033.
[Tree]
InterProIPR006009. GlcNAc_MurG.
IPR004276. Glyco_trans_28.
IPR007235. Glyco_trans_28_C.
[Graphical view]
PfamPF04101. Glyco_tran_28_C. 1 hit.
PF03033. Glyco_transf_28. 1 hit.
[Graphical view]
TIGRFAMsTIGR01133. murG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMURG_BORBZ
AccessionPrimary (citable) accession number: B7J0L2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: October 13, 2009
This is version 8 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents