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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Borrelia burgdorferi (strain ZS7)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei387 – 3871UniRule annotation
Active sitei502 – 5021UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciBBUR445985:GKEU-751-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:BbuZS7_0755
OrganismiBorrelia burgdorferi (strain ZS7)
Taxonomic identifieri445985 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group
ProteomesiUP000006901: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 530530Glucose-6-phosphate isomerasePRO_1000125696Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi445985.BbuZS7_0755.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7J0H6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNYKNLNEL ENFKILEGIA PEVLKTALTG KRIKEYDITI EGDSVHYNYA
60 70 80 90 100
SKQINETHLK IFQNLSDEAN LIEKYKEVLD GEKINISENR KVLHHLTRGQ
110 120 130 140 150
IGKDVIEDNK ENMREFFQSE LEKIYNFAKQ IHSGNIKSSN GKKFKNVVQI
160 170 180 190 200
GIGGSSLGPK ALYSSIKNYA KKHNLALMNG YFISNIDPDE SEEVLSSINV
210 220 230 240 250
DETLFIIVSK SGNTLETKAN MQFLINKLKL NGIKEYKKQM VIITLKDSML
260 270 280 290 300
AIEEKGYLEY FFMHDSIGGR FSPTSAVGLT LLTLCFTEKV AKEILKGANE
310 320 330 340 350
ADKKSLNKNV KDNASLLAAL ISIYERNVLN YSSNCIIAYS KAMENFYLHL
360 370 380 390 400
QQLEMESNGK SVNRFNETIN YKTVRIIWGG IGTDVQHSFF QMLHQGTDIV
410 420 430 440 450
PMDFIGFNET QLKEDVISDN SSSNDKLKAN LIAQIIAFSK GKENSNKNKN
460 470 480 490 500
FQGERPSALI YSKELTPYAI GAILSHYENK VMFEGFLLNI NSFDQEGVQL
510 520 530
GKIIANQILK NDNFKDEVIE SYSKKILKKF
Length:530
Mass (Da):60,121
Last modified:February 10, 2009 - v1
Checksum:i15C0F8B0CB6AE312
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001205 Genomic DNA. Translation: ACK74544.1.
RefSeqiYP_002375229.1. NC_011728.1.

Genome annotation databases

EnsemblBacteriaiACK74544; ACK74544; BbuZS7_0755.
GeneIDi7106587.
KEGGibbz:BbuZS7_0755.
PATRICi20560937. VBIBorBur54821_0862.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001205 Genomic DNA. Translation: ACK74544.1.
RefSeqiYP_002375229.1. NC_011728.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi445985.BbuZS7_0755.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACK74544; ACK74544; BbuZS7_0755.
GeneIDi7106587.
KEGGibbz:BbuZS7_0755.
PATRICi20560937. VBIBorBur54821_0862.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciBBUR445985:GKEU-751-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ZS7.

Entry informationi

Entry nameiG6PI_BORBZ
AccessioniPrimary (citable) accession number: B7J0H6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: January 7, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.