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B7IWP5 (B7IWP5_BACC2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Arginine biosynthesis bifunctional protein ArgJ HAMAP MF_01106
Gene names
Name:argJ HAMAP MF_01106 EMBL ACK95347.1
Ordered Locus Names:BCG9842_B0995
OrganismBacillus cereus (strain G9842) [Complete proteome] [HAMAP]
Taxonomic identifier405531 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length407 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate By similarity. HAMAP MF_01106

Catalytic activity

Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate. HAMAP MF_01106

N(2)-acetyl-L-ornithine + L-glutamate = L-ornithine + N-acetyl-L-glutamate. HAMAP MF_01106

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1. HAMAP MF_01106

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. HAMAP MF_01106

Subunit structure

Heterotetramer of two alpha and two beta chains By similarity. HAMAP MF_01106

Subcellular location

Cytoplasm By similarity HAMAP MF_01106.

Miscellaneous

Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway By similarity. HAMAP MF_01106

Sequence similarities

Belongs to the ArgJ family. HAMAP MF_01106

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Site193 – 1942Cleavage; by autolysis By similarity HAMAP MF_01106

Sequences

Sequence LengthMass (Da)Tools
B7IWP5 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 41BA602DCE5B611F

FASTA40743,876
        10         20         30         40         50         60 
MIKVASITKL ENGSIVTPKG FSAIGTANGL KKEKKDLGAI VCDVPASCAA VYTTNQIQAA 

        70         80         90        100        110        120 
PLQVTKDSIT AEGKLQAIIV NSGNANACTG MKGLQDAYEM RALGAEHFGM KENYVAVAST 

       130        140        150        160        170        180 
GVIGVPLPMD IIRKGVATLI PTKEESEAYC FSEAILTTDL IMKETCYEMI IDGKKVAIAG 

       190        200        210        220        230        240 
VAKGSGMIHP NMATMLSFIT TDAHIEHDVL QTALSEITNH TFNQITVDGD TSTNDMVIVM 

       250        260        270        280        290        300 
ASGLSETRPI NMEHTDWETF VCALQQVCED LAKKIAQDGE GATKLIEVNV LGAQTNEEAK 

       310        320        330        340        350        360 
KIAKQIVGSS LVKTAIHGED PNWGRIISSI GQSEVAIHPN TIDITLQSIS VLKNSEPQIF 

       370        380        390        400 
SEEEMKERLQ EDEIVINVYL HLGEETGSAW GCDLSYEYVK INACYRT 

« Hide

References

[1]"Genome sequence of Bacillus cereus G9842."
Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A., Ravel J., Sutton G.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001186 Genomic DNA. Translation: ACK95347.1.
RefSeqYP_002447705.1. NC_011772.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB7IWP5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000105233; EBBACP00000100854; EBBACG00000105226.
GeneID7182589.
GenomeReviewsGene locus BCG9842_B0995 in contig CP001186_GR.
KEGGbcg:BCG9842_B0995.
PATRIC18904015. VBIBacCer50903_4159.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000002382.
HOGENOMHBG284202.
OMAGRDPNWG.
ProtClustDBPRK05388.

Family and domain databases

HAMAPMF_01106. ArgJ.
[Tree]
InterProIPR002813. Arg_biosynth_ArgJ.
IPR016117. Pept_S58_DmpA/Arg_biosyn_ArgJ.
[Graphical view]
KOK00620.
PANTHERPTHR23100. ArgJ. 1 hit.
PfamPF01960. ArgJ. 1 hit.
[Graphical view]
ProDomPD004193. Arg_biosynth_ArgJ. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56266. Pept_S58_DmpA/Arg_biosyn_ArgJ. 1 hit.
TIGRFAMsTIGR00120. ArgJ. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB7IWP5_BACC2
AccessionPrimary (citable) accession number: B7IWP5
Entry history
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)