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Protein

Pseudouridine synthase

Gene

BCG9842_B1248

Organism
Bacillus cereus (strain G9842)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil.UniRule annotation

Catalytic activityi

RNA uridine = RNA pseudouridine.UniRule annotation

GO - Molecular functioni

  1. pseudouridine synthase activity Source: InterPro
  2. RNA binding Source: InterPro

GO - Biological processi

  1. pseudouridine synthesis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Enzyme and pathway databases

BioCyciBCER405531:GI5L-4013-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pseudouridine synthaseUniRule annotation (EC:5.4.99.-UniRule annotation)
Gene namesi
Ordered Locus Names:BCG9842_B1248Imported
OrganismiBacillus cereus (strain G9842)Imported
Taxonomic identifieri405531 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000006744 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi405531.BCG9842_B1248.

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase RluA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0564.
HOGENOMiHOG000275919.
KOiK06180.
OMAiTYGGRPR.
OrthoDBiEOG6P070X.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00005. rluA_subfam. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7IUQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEVVQVTVV EEQKNERIDK FVAGINNEWS RSQVQQWIKD DVVTVNGKAV
60 70 80 90 100
KVNYKVKEED EITVTIPDPE ALDIQPEDMN LEIYYEDADV LVVNKPRGMV
110 120 130 140 150
VHPAPGHTSG TLVNGLMHHC TDLSGINGVM RPGIVHRIDK DTSGLLMVAK
160 170 180 190 200
NDMAHESLVN QLVAKTVTRR YKAIVHGVIP HDKGTIDAPI GRDKKERQSM
210 220 230 240 250
TVDENGKNAV THFQVLERFK DFTLVECRLE TGRTHQIRVH MKYIGYPLAG
260 270 280 290 300
DPKYGPKKTL DMNGQALHAG ILGFDHPRTG EYIQFEAPIP EVFEEALNIL

RK
Length:302
Mass (Da):33,975
Last modified:February 9, 2009 - v1
Checksum:i07B5C0F853B3CA18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001186 Genomic DNA. Translation: ACK95893.1.
RefSeqiYP_002447457.1. NC_011772.1.

Genome annotation databases

EnsemblBacteriaiACK95893; ACK95893; BCG9842_B1248.
KEGGibcg:BCG9842_B1248.
PATRICi18903514. VBIBacCer50903_3909.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001186 Genomic DNA. Translation: ACK95893.1.
RefSeqiYP_002447457.1. NC_011772.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi405531.BCG9842_B1248.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACK95893; ACK95893; BCG9842_B1248.
KEGGibcg:BCG9842_B1248.
PATRICi18903514. VBIBacCer50903_3909.

Phylogenomic databases

eggNOGiCOG0564.
HOGENOMiHOG000275919.
KOiK06180.
OMAiTYGGRPR.
OrthoDBiEOG6P070X.

Enzyme and pathway databases

BioCyciBCER405531:GI5L-4013-MONOMER.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00005. rluA_subfam. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Bacillus cereus G9842."
    Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A., Ravel J., Sutton G.
    Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: G9842Imported.

Entry informationi

Entry nameiB7IUQ2_BACC2
AccessioniPrimary (citable) accession number: B7IUQ2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 9, 2009
Last sequence update: February 9, 2009
Last modified: March 31, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.