B7IRD8 (B7IRD8_BACC2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA1 EMBL ACK93835.1
Synonyms:	msrA HAMAP MF_01401
Ordered Locus Names:	BCG9842_B3494

Organism

Bacillus cereus (strain G9842) [Complete proteome] [HAMAP]

Taxonomic identifier

405531 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569 EMBL ACK93835.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	15	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	B7IRD8 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 3CC1554C32F8E41B	FASTA	178	20,508
	10 20 30 40 50 60 MSEKTYELAT FAGGCFWCMV KPFDELPGIH KVLSGYAGGH VENPTYEQVK TGTSGHLEVV 70 80 90 100 110 120 QITFDPSIFP YQKLLDLYWP QIDPTDDGGQ FFDRGPSYRT AIFYHNETQK GLAEKSKQAL 130 140 150 160 170 AESSMFKDPI VTEIRPAAPF YEADDYHQHF YKKNPEKYAT EQKESGREDF IKENWQKK

References

[1]	"Genome sequence of Bacillus cereus G9842." Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A., Ravel J., Sutton G. Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001186 Genomic DNA. Translation: ACK93835.1.
RefSeq	YP_002445228.1. NC_011772.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B7IRD8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000101615; EBBACP00000099136; EBBACG00000101608.
GeneID	7185696.
GenomeReviews	Gene locus BCG9842_B3494 in contig CP001186_GR.
KEGG	bcg:BCG9842_B3494.
PATRIC	18899065. VBIBacCer50903_1688.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000000580.
HOGENOM	HBG748152.
OMA	LVELYWT.
ProtClustDB	CLSK916383.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B7IRD8_BACC2

Accession

Primary (citable) accession number: B7IRD8

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)