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Protein

ATP-dependent Clp protease ATP-binding subunit ClpX

Gene

clpX

Organism
Bacillus cereus (strain G9842)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri13 – 38C4-typeUniRule annotationAdd BLAST26
Nucleotide bindingi117 – 124ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent Clp protease ATP-binding subunit ClpXUniRule annotation
Gene namesi
Name:clpXUniRule annotation
Ordered Locus Names:BCG9842_B0644
OrganismiBacillus cereus (strain G9842)
Taxonomic identifieri405531 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000006744 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001896821 – 419ATP-dependent Clp protease ATP-binding subunit ClpXAdd BLAST419

Interactioni

Subunit structurei

Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.UniRule annotation

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB7IIY3
SMRiB7IIY3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ClpX chaperone family.UniRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri13 – 38C4-typeUniRule annotationAdd BLAST26

Keywords - Domaini

Zinc-finger

Phylogenomic databases

HOGENOMiHOG000010093
KOiK03544
OMAiDIMYDLP

Family and domain databases

Gene3Di3.30.50.30, 1 hit
HAMAPiMF_00175 ClpX, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR019489 Clp_ATPase_C
IPR004487 Clp_protease_ATP-bd_su_ClpX
IPR027417 P-loop_NTPase
IPR010603 Znf_CppX_C4
IPR038366 Znf_CppX_C4_sf
PANTHERiPTHR11262 PTHR11262, 2 hits
PfamiView protein in Pfam
PF07724 AAA_2, 1 hit
PF10431 ClpB_D2-small, 1 hit
PF06689 zf-C4_ClpX, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM01086 ClpB_D2-small, 1 hit
SM00994 zf-C4_ClpX, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00382 clpX, 1 hit

Sequencei

Sequence statusi: Complete.

B7IIY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKFNDEKGQ LKCSFCGKTQ TQVRKLVAGP GVYICDECIE LCTEIVQEEL
60 70 80 90 100
AKDEEVEFKD VPKPVEIREI LDEYVIGQDS AKKALAVAVY NHYKRINSNS
110 120 130 140 150
KIDDVELAKS NIALIGPTGS GKTLLAQTLA RILNVPFAIA DATSLTEAGY
160 170 180 190 200
VGEDVENILL KLIQAADYDV EKAEKGIIYI DEIDKVARKS ENPSITRDVS
210 220 230 240 250
GEGVQQALLK ILEGTVASVP PQGGRKHPHQ EFIQIDTTNI LFICGGAFDG
260 270 280 290 300
IEPIIKRRLG EKVIGFGSEK KNADVNEKHV LSHVLPEDLL RFGLIPEFIG
310 320 330 340 350
RLPVIANLEP LDEDALVDIL TKPKNALVKQ FQKLLELDDV ELEFEEGALI
360 370 380 390 400
EIAKKAIERK TGARGLRSII EGLMLDVMFE LPSRKDIEKC ILTKETVADN
410
EPPKLVLQDG TVLDTKTSA
Length:419
Mass (Da):46,242
Last modified:February 10, 2009 - v1
Checksum:iCEEB7832141536FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001186 Genomic DNA Translation: ACK95053.1
RefSeqiWP_000472289.1, NC_011772.1

Genome annotation databases

EnsemblBacteriaiACK95053; ACK95053; BCG9842_B0644
GeneIDi31628072
KEGGibcg:BCG9842_B0644

Similar proteinsi

Entry informationi

Entry nameiCLPX_BACC2
AccessioniPrimary (citable) accession number: B7IIY3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: March 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health