B7IFD9 (B7IFD9_THEAB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
NH(3)-dependent NAD(+) synthetase RuleBase RU003812
EC=6.3.1.5 RuleBase RU003812

Gene names

Name:	nadE1 EMBL ACJ74803.1
Ordered Locus Names:	THA_303

Organism

Thermosipho africanus (strain TCF52B) [Complete proteome] [HAMAP]

Taxonomic identifier

484019 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermosipho

Protein attributes

Sequence length	290 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+. RuleBase RU003812 SAAS SAAS003694
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1. RuleBase RU004252 SAAS SAAS003694
Sequence similarities	Belongs to the NAD synthetase family. RuleBase RU003811

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU003811 SAAS SAAS003694 NAD SAAS SAAS003694 RuleBase RU003811 Nucleotide-binding
Molecular function	Ligase SAAS SAAS003694 RuleBase RU003811
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ synthase (glutamine-hydrolyzing) activity Inferred from electronic annotation. Source: InterPro NAD+ synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7IFD9 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 658AFC8F015A2BB9	FASTA	290	33,646
	10 20 30 40 50 60 MTKKSEKIVN FLRETVAQYN FRGLVLGVSG GLDSAVVLAL LVKAFDRDKI KCFILPERDS 70 80 90 100 110 120 PKDSVKDAVF VCKYFGVEYE IKNITKILRA LGIYKYYPPA FFVPWKVKEN FAKKRWQKYK 130 140 150 160 170 180 EKGNPFEFDI EGIEDEEFLK GISYYRAKHR VRMVYLYKEA ERRNYAVVGT TNKTEFLTGL 190 200 210 220 230 240 YVKWGDDSTD IEPILHLYKT QVYELAKELN VPEKIIMKPA SPDLIPGIGD EEIFGLDYST 250 260 270 280 290 LDRILDKLLN NKSLDGEDPE KVKLVKRLYQ IGKKRNSLRN VSMVDDLYGT

References

[1]

"The genome of Thermosipho africanus TCF52B: lateral genetic connections to the Firmicutes and Archaea." Nesboe C.L., Bapteste E., Curtis B., Dahle H., Lopez P., Macleod D., Dlutek M., Bowman S., Zhaxybayeva O., Birkeland N.-K., Doolittle W.F. J. Bacteriol. 191:1974-1978(2009) [PubMed: 19124572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001185 Genomic DNA. Translation: ACJ74803.1.
RefSeq	YP_002334144.1. NC_011653.1.
3D structure databases
ProteinModelPortal	B7IFD9.
ModBase	Search...
Protein-protein interaction databases
STRING	B7IFD9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7071189.
GenomeReviews	Gene locus THA_303 in contig CP001185_GR.
KEGG	taf:THA_303.
PATRIC	23917536. VBITheAfr129358_0308.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG351567.
OMA	DGAVDCH.
ProtClustDB	CLSK875266.
Family and domain databases
InterPro	IPR022310. NAD/GMP_synthase. IPR003694. NAD_synthase. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K01916.
Pfam	PF02540. NAD_synthase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00552. NadE. 2 hits.
ProtoNet	Search...

Entry information

Entry name

B7IFD9_THEAB

Accession

Primary (citable) accession number: B7IFD9

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)