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B7IFD0

- GLGA_THEAB

UniProt

B7IFD0 - GLGA_THEAB

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Protein

Glycogen synthase

Gene

glgA

Organism
Thermosipho africanus (strain TCF52B)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciTAFR484019:GJOH-300-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:THA_294
OrganismiThermosipho africanus (strain TCF52B)
Taxonomic identifieri484019 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermosipho
ProteomesiUP000002453: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 485485Glycogen synthasePRO_1000126108Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi484019.THA_294.

Structurei

3D structure databases

ProteinModelPortaliB7IFD0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiHEMVQNC.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

B7IFD0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKVALVSYEV YPFAKVGGLA DVVGALPKYL KNFSVEPIVI MPKHKIVEKN
60 70 80 90 100
AEKFSYSLRK IKESISVPYL KTDEKFDIYQ TFIPGTQIPV YLIANDYYFS
110 120 130 140 150
AEQVYEGPDL AEQAIYFSAA VFEALKVLGE KVDVLHINDW QTGLVPVYLK
160 170 180 190 200
TLYKDDEFFS KTVVLLTIHN LGYQGIFDSS YMNFSGLPDY LYNIDGIEFY
210 220 230 240 250
GKINFLKGGI LFSDVINTVS PTYAQEIQTK EYGEKLDGVL RLRSSDLYGI
260 270 280 290 300
LNGIDYDEYN PETDKRIYVN YSLQEIEKKY ENKKMLQKEL NLPQTNDVPV
310 320 330 340 350
IGMITRLVDQ KGLDILSEVL RYILNMDVQF VLLGTGDKKY EEMFKDIEKE
360 370 380 390 400
FPDKMSANIT FDIVLAQKIY ASSDMFLMPS RYEPCGLGQM YSLRYGTIPV
410 420 430 440 450
VRYTGGLADT VMEYDEEAMK GNGFGFKEYD SAYLLKAVAR AVDFFKNKKG
460 470 480
HWKKLIENAM KTDLSWERSA NEYVKIYNKA LNKRR
Length:485
Mass (Da):55,785
Last modified:February 10, 2009 - v1
Checksum:i22D43DA6A5F7FA6F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001185 Genomic DNA. Translation: ACJ74794.1.
RefSeqiYP_002334135.1. NC_011653.1.

Genome annotation databases

EnsemblBacteriaiACJ74794; ACJ74794; THA_294.
GeneIDi7071180.
KEGGitaf:THA_294.
PATRICi23917518. VBITheAfr129358_0299.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001185 Genomic DNA. Translation: ACJ74794.1 .
RefSeqi YP_002334135.1. NC_011653.1.

3D structure databases

ProteinModelPortali B7IFD0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 484019.THA_294.

Protein family/group databases

CAZyi GT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACJ74794 ; ACJ74794 ; THA_294 .
GeneIDi 7071180.
KEGGi taf:THA_294.
PATRICi 23917518. VBITheAfr129358_0299.

Phylogenomic databases

eggNOGi COG0297.
HOGENOMi HOG000294940.
KOi K00703.
OMAi HEMVQNC.
OrthoDBi EOG6JTC6Z.

Enzyme and pathway databases

UniPathwayi UPA00164 .
BioCyci TAFR484019:GJOH-300-MONOMER.

Family and domain databases

HAMAPi MF_00484. Glycogen_synth.
InterProi IPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view ]
Pfami PF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02095. glgA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome of Thermosipho africanus TCF52B: lateral genetic connections to the Firmicutes and Archaea."
    Nesboe C.L., Bapteste E., Curtis B., Dahle H., Lopez P., Macleod D., Dlutek M., Bowman S., Zhaxybayeva O., Birkeland N.-K., Doolittle W.F.
    J. Bacteriol. 191:1974-1978(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TCF52B.

Entry informationi

Entry nameiGLGA_THEAB
AccessioniPrimary (citable) accession number: B7IFD0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: October 1, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3