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B7IFD0

- GLGA_THEAB

UniProt

B7IFD0 - GLGA_THEAB

Protein

Glycogen synthase

Gene

glgA

Organism
Thermosipho africanus (strain TCF52B)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (10 Feb 2009)
      Previous versions | rss
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    Functioni

    Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

    Catalytic activityi

    ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei15 – 151ADP-glucoseUniRule annotation

    GO - Molecular functioni

    1. starch synthase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycogen biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Glycogen biosynthesis

    Enzyme and pathway databases

    BioCyciTAFR484019:GJOH-300-MONOMER.
    UniPathwayiUPA00164.

    Protein family/group databases

    CAZyiGT5. Glycosyltransferase Family 5.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
    Alternative name(s):
    Starch [bacterial glycogen] synthaseUniRule annotation
    Gene namesi
    Name:glgAUniRule annotation
    Ordered Locus Names:THA_294
    OrganismiThermosipho africanus (strain TCF52B)
    Taxonomic identifieri484019 [NCBI]
    Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermosipho
    ProteomesiUP000002453: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 485485Glycogen synthasePRO_1000126108Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi484019.THA_294.

    Structurei

    3D structure databases

    ProteinModelPortaliB7IFD0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0297.
    HOGENOMiHOG000294940.
    KOiK00703.
    OMAiHEMVQNC.
    OrthoDBiEOG6JTC6Z.

    Family and domain databases

    HAMAPiMF_00484. Glycogen_synth.
    InterProiIPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view]
    PfamiPF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02095. glgA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B7IFD0-1 [UniParc]FASTAAdd to Basket

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    MKVALVSYEV YPFAKVGGLA DVVGALPKYL KNFSVEPIVI MPKHKIVEKN    50
    AEKFSYSLRK IKESISVPYL KTDEKFDIYQ TFIPGTQIPV YLIANDYYFS 100
    AEQVYEGPDL AEQAIYFSAA VFEALKVLGE KVDVLHINDW QTGLVPVYLK 150
    TLYKDDEFFS KTVVLLTIHN LGYQGIFDSS YMNFSGLPDY LYNIDGIEFY 200
    GKINFLKGGI LFSDVINTVS PTYAQEIQTK EYGEKLDGVL RLRSSDLYGI 250
    LNGIDYDEYN PETDKRIYVN YSLQEIEKKY ENKKMLQKEL NLPQTNDVPV 300
    IGMITRLVDQ KGLDILSEVL RYILNMDVQF VLLGTGDKKY EEMFKDIEKE 350
    FPDKMSANIT FDIVLAQKIY ASSDMFLMPS RYEPCGLGQM YSLRYGTIPV 400
    VRYTGGLADT VMEYDEEAMK GNGFGFKEYD SAYLLKAVAR AVDFFKNKKG 450
    HWKKLIENAM KTDLSWERSA NEYVKIYNKA LNKRR 485
    Length:485
    Mass (Da):55,785
    Last modified:February 10, 2009 - v1
    Checksum:i22D43DA6A5F7FA6F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001185 Genomic DNA. Translation: ACJ74794.1.
    RefSeqiYP_002334135.1. NC_011653.1.

    Genome annotation databases

    EnsemblBacteriaiACJ74794; ACJ74794; THA_294.
    GeneIDi7071180.
    KEGGitaf:THA_294.
    PATRICi23917518. VBITheAfr129358_0299.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001185 Genomic DNA. Translation: ACJ74794.1 .
    RefSeqi YP_002334135.1. NC_011653.1.

    3D structure databases

    ProteinModelPortali B7IFD0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 484019.THA_294.

    Protein family/group databases

    CAZyi GT5. Glycosyltransferase Family 5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACJ74794 ; ACJ74794 ; THA_294 .
    GeneIDi 7071180.
    KEGGi taf:THA_294.
    PATRICi 23917518. VBITheAfr129358_0299.

    Phylogenomic databases

    eggNOGi COG0297.
    HOGENOMi HOG000294940.
    KOi K00703.
    OMAi HEMVQNC.
    OrthoDBi EOG6JTC6Z.

    Enzyme and pathway databases

    UniPathwayi UPA00164 .
    BioCyci TAFR484019:GJOH-300-MONOMER.

    Family and domain databases

    HAMAPi MF_00484. Glycogen_synth.
    InterProi IPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view ]
    Pfami PF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02095. glgA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome of Thermosipho africanus TCF52B: lateral genetic connections to the Firmicutes and Archaea."
      Nesboe C.L., Bapteste E., Curtis B., Dahle H., Lopez P., Macleod D., Dlutek M., Bowman S., Zhaxybayeva O., Birkeland N.-K., Doolittle W.F.
      J. Bacteriol. 191:1974-1978(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TCF52B.

    Entry informationi

    Entry nameiGLGA_THEAB
    AccessioniPrimary (citable) accession number: B7IFD0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: February 10, 2009
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3