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Protein

Glycogen synthase

Gene

glgA

Organism
Thermosipho africanus (strain TCF52B)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathway:iglycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciTAFR484019:GJOH-300-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:THA_294
OrganismiThermosipho africanus (strain TCF52B)
Taxonomic identifieri484019 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesFervidobacteriaceaeThermosipho
ProteomesiUP000002453 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 485485Glycogen synthasePRO_1000126108Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi484019.THA_294.

Structurei

3D structure databases

ProteinModelPortaliB7IFD0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiNLQINGM.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

B7IFD0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVALVSYEV YPFAKVGGLA DVVGALPKYL KNFSVEPIVI MPKHKIVEKN
60 70 80 90 100
AEKFSYSLRK IKESISVPYL KTDEKFDIYQ TFIPGTQIPV YLIANDYYFS
110 120 130 140 150
AEQVYEGPDL AEQAIYFSAA VFEALKVLGE KVDVLHINDW QTGLVPVYLK
160 170 180 190 200
TLYKDDEFFS KTVVLLTIHN LGYQGIFDSS YMNFSGLPDY LYNIDGIEFY
210 220 230 240 250
GKINFLKGGI LFSDVINTVS PTYAQEIQTK EYGEKLDGVL RLRSSDLYGI
260 270 280 290 300
LNGIDYDEYN PETDKRIYVN YSLQEIEKKY ENKKMLQKEL NLPQTNDVPV
310 320 330 340 350
IGMITRLVDQ KGLDILSEVL RYILNMDVQF VLLGTGDKKY EEMFKDIEKE
360 370 380 390 400
FPDKMSANIT FDIVLAQKIY ASSDMFLMPS RYEPCGLGQM YSLRYGTIPV
410 420 430 440 450
VRYTGGLADT VMEYDEEAMK GNGFGFKEYD SAYLLKAVAR AVDFFKNKKG
460 470 480
HWKKLIENAM KTDLSWERSA NEYVKIYNKA LNKRR
Length:485
Mass (Da):55,785
Last modified:February 10, 2009 - v1
Checksum:i22D43DA6A5F7FA6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001185 Genomic DNA. Translation: ACJ74794.1.
RefSeqiWP_012579478.1. NC_011653.1.

Genome annotation databases

EnsemblBacteriaiACJ74794; ACJ74794; THA_294.
KEGGitaf:THA_294.
PATRICi23917518. VBITheAfr129358_0299.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001185 Genomic DNA. Translation: ACJ74794.1.
RefSeqiWP_012579478.1. NC_011653.1.

3D structure databases

ProteinModelPortaliB7IFD0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi484019.THA_294.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACJ74794; ACJ74794; THA_294.
KEGGitaf:THA_294.
PATRICi23917518. VBITheAfr129358_0299.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiNLQINGM.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciTAFR484019:GJOH-300-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome of Thermosipho africanus TCF52B: lateral genetic connections to the Firmicutes and Archaea."
    Nesboe C.L., Bapteste E., Curtis B., Dahle H., Lopez P., Macleod D., Dlutek M., Bowman S., Zhaxybayeva O., Birkeland N.-K., Doolittle W.F.
    J. Bacteriol. 191:1974-1978(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TCF52B.

Entry informationi

Entry nameiGLGA_THEAB
AccessioniPrimary (citable) accession number: B7IFD0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: July 22, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.