B7IE29 (TAL_THEAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	THA_1825

Organism

Thermosipho africanus (strain TCF52B) [Complete proteome] [HAMAP]

Taxonomic identifier

484019 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermosipho

Protein attributes

Sequence length	216 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00494
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00494
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00494
Subcellular location	Cytoplasm By similarity HAMAP MF_00494.
Sequence similarities	Belongs to the transaldolase family. Type 3B subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 216	216	Probable transaldolase HAMAP MF_00494		PRO_1000126365
Sites
	Active site	83	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	B7IE29 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 881BDD620C61F7E9	FASTA	216	23,932
	10 20 30 40 50 60 MKIFLDTANL DEIRRGVEWG VVDGVTTNPT LISKEGKPFE ETIKEICNIV QGPISAEVIS 70 80 90 100 110 120 LNFEGMIDEA RNLAKIDENI VIKIPMTPNG IKAVKVLSKE GIKTNVTLIF SPNQALLAAK 130 140 150 160 170 180 AGATYVSPFV GRVDDLANDG LKIVEEIMQI YENYGFETEV IVASVRHPMH VLEAALIGAD 190 200 210 IATVPFSVLE KMFKHPMTDI GIERFLKDWE KYKTGR

References

[1]

"The genome of Thermosipho africanus TCF52B: lateral genetic connections to the Firmicutes and Archaea." Nesboe C.L., Bapteste E., Curtis B., Dahle H., Lopez P., Macleod D., Dlutek M., Bowman S., Zhaxybayeva O., Birkeland N.-K., Doolittle W.F. J. Bacteriol. 191:1974-1978(2009) [PubMed: 19124572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TCF52B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001185 Genomic DNA. Translation: ACJ76256.1.
RefSeq	YP_002335597.1. NC_011653.1.
3D structure databases
ProteinModelPortal	B7IE29.
ModBase	Search...
Protein-protein interaction databases
STRING	B7IE29.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7071575.
GenomeReviews	Gene locus THA_1825 in contig CP001185_GR.
KEGG	taf:THA_1825.
PATRIC	23920704. VBITheAfr129358_1847.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG533000.
OMA	KVNVTLC.
ProtClustDB	PRK01362.
Family and domain databases
HAMAP	MF_00494. Transaldolase_3b. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004731. Transaldolase_3A/3B. IPR022999. Transaldolase_3B. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00875. Fsa_talC_mipB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_THEAB

Accession

Primary (citable) accession number: B7IE29

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program