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B7IDT4 (APGM_THEAB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1
Gene names
Name:apgM
Ordered Locus Names:THA_1725
OrganismThermosipho africanus (strain TCF52B) [Complete proteome] [HAMAP]
Taxonomic identifier484019 [NCBI]
Taxonomic lineageBacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermosipho

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_B

Catalytic activity

2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_B

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_B

Sequence similarities

Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
   Biological processGlycolysis
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: InterPro

phosphoglycerate mutase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 402402Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_B
PRO_1000145451

Sequences

Sequence LengthMass (Da)Tools
B7IDT4 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: A1C9F344008E31C0

FASTA40244,498
        10         20         30         40         50         60 
MIDRQKVISE LISPNTSKIV LLVMDGIGDI PNEEGLTPLQ KANTPNLDAL AKKSDLGQTI 

        70         80         90        100        110        120 
PVLPGITPGS GPGHLGLFGY DPLKYQIGRG ILEALGINVE VGENDLVARG NFATIDGDII 

       130        140        150        160        170        180 
VDRRAGRPSS EESAKVVEIL NENIKEIEDV KITFYPGKEH RFVVKFTGEG LMDKLEDADP 

       190        200        210        220        230        240 
QKEGKPIKYT KALDESSKKS ERIVNILLDK IKEVLKDQPK MNFALLRGFS KHPDMPKFGD 

       250        260        270        280        290        300 
VFKLKPAAVA VYPMYKGLAK LVGMEVVEAG QTIEDEFNTV KKLWNEYDFF YVHIKKTDSY 

       310        320        330        340        350        360 
GEDGNFDSKV KVIEEVDKFL PILLELNPDV LIVTGDHSTP CVMKGHSFHP VPLMIYAKNT 

       370        380        390        400 
RRGLSKLFNE FECARGSLGT IHAVDVMPLA LAYAGRLEKY GA

« Hide

References

[1]"The genome of Thermosipho africanus TCF52B: lateral genetic connections to the Firmicutes and Archaea."
Nesboe C.L., Bapteste E., Curtis B., Dahle H., Lopez P., Macleod D., Dlutek M., Bowman S., Zhaxybayeva O., Birkeland N.-K., Doolittle W.F.
J. Bacteriol. 191:1974-1978(2009) [PubMed: 19124572] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TCF52B.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001185 Genomic DNA. Translation: ACJ76161.1.
RefSeqYP_002335502.1. NC_011653.1.

3D structure databases

ProteinModelPortalB7IDT4.
ModBaseSearch...

Protein-protein interaction databases

STRINGB7IDT4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7072062.
GenomeReviewsGene locus THA_1725 in contig CP001185_GR.
KEGGtaf:THA_1725.
PATRIC23920501. VBITheAfr129358_1750.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG463247.
OMADIAFRCN.
ProtClustDBPRK04135.

Family and domain databases

HAMAPMF_01402_B. ApgM_B.
[Tree]
InterProIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR023665. ApgAM.
IPR004456. BisP-indep_Pglycerate_Mutase.
IPR006124. Metalloenzyme.
[Graphical view]
Gene3DG3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KOK15635.
PfamPF01676. Metalloenzyme. 1 hit.
PF10143. PhosphMutase. 1 hit.
[Graphical view]
PIRSFPIRSF006392. IPGAM_arch. 1 hit.
SUPFAMSSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMsTIGR00306. ApgM. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAPGM_THEAB
AccessionPrimary (citable) accession number: B7IDT4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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