B7IDS9 (B7IDS9_THEAB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamine-dependent NAD+ synthetase EMBL ACJ76156.1

Gene names

Name:	nadE2 EMBL ACJ76156.1
Ordered Locus Names:	THA_1720

Organism

Thermosipho africanus (strain TCF52B) [Complete proteome] [HAMAP]

Taxonomic identifier

484019 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermosipho

Protein attributes

Sequence length	576 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the NAD synthetase family. RuleBase RU003811

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU003811 SAAS SAAS003694 NAD RuleBase RU003811 SAAS SAAS003694 Nucleotide-binding
Molecular function	Ligase SAAS SAAS003694 RuleBase RU003811
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ synthase (glutamine-hydrolyzing) activity Inferred from electronic annotation. Source: InterPro hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7IDS9 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: E97A57C1A2004CA9	FASTA	576	65,981
	10 20 30 40 50 60 MYIRTTVAQL NSTLGDFEGN MKKIISAIEI AENNNSEFLI FPELFLTGYP PEDLILRTSF 70 80 90 100 110 120 LKKNIEYLEK IINFSRGKNV IILLGFIDIE DDAYNSLAVI RDGKLLGKYH KMHLPNYSVF 130 140 150 160 170 180 DENRYFKSGN EIVIINYNNI KIGINICEDI WSPLGPMFYQ AINGAQLILN ASASPYFHGK 190 200 210 220 230 240 RELRKNYLSK KSYDHHCPIV YCNMVGGQDE VVFDGGSVVT SSDGKIIFEG KPFEEEIFTI 250 260 270 280 290 300 DIPIEDNLRT NLHDPRRRYI NIVNDKPINY IFVKSENINK LKPINYKNKN YTLTKEEEIF 310 320 330 340 350 360 RAITLGLKDY IQKNGFKKVL IGLSGGMDSS LVAAIAVEAL GNKNVVGILM PSMYSSSHSI 370 380 390 400 410 420 EDAKKLAENL EIEYHIIKIS DIYYSFKNSL KDIFKGTSED ITEENLQARI RGTLLMAVSN 430 440 450 460 470 480 KFGYIVLATG NKSEIATGYS TLYGDMVGGF SPIKDIYKTD VYKIARWYNK FKGKEIIPEN 490 500 510 520 530 540 VFIKPPSAEL RPDQKDQDTL PPYEILDEIL KMYIEKELSV DEIINKGFDK DTVKYVAKLV 550 560 570 DRNEYKRRQG VIGVKVSERS FGKDRRMPIT NKYREW

References

[1]

"The genome of Thermosipho africanus TCF52B: lateral genetic connections to the Firmicutes and Archaea." Nesboe C.L., Bapteste E., Curtis B., Dahle H., Lopez P., Macleod D., Dlutek M., Bowman S., Zhaxybayeva O., Birkeland N.-K., Doolittle W.F. J. Bacteriol. 191:1974-1978(2009) [PubMed: 19124572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001185 Genomic DNA. Translation: ACJ76156.1.
RefSeq	YP_002335497.1. NC_011653.1.
3D structure databases
ProteinModelPortal	B7IDS9.
ModBase	Search...
Protein-protein interaction databases
STRING	B7IDS9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7072057.
GenomeReviews	Gene locus THA_1720 in contig CP001185_GR.
KEGG	taf:THA_1720.
PATRIC	23920491. VBITheAfr129358_1745.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG691171.
OMA	KISHKAF.
ProtClustDB	PRK13981.
Family and domain databases
InterPro	IPR014445. Gln-dep_NAD_synthase. IPR022310. NAD/GMP_synthase. IPR003694. NAD_synthase. IPR003010. Ntlse/CNhydtse. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.60.110.10. Ntlse/CNhydtse. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KO	K01950.
Pfam	PF00795. CN_hydrolase. 1 hit. PF02540. NAD_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF006630. NADS_GAT. 1 hit.
SUPFAM	SSF56317. Ntlse/CNhydtse. 1 hit.
TIGRFAMs	TIGR00552. NadE. 1 hit.
PROSITE	PS50263. CN_HYDROLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B7IDS9_THEAB

Accession

Primary (citable) accession number: B7IDS9

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)