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B7ICM4 (B7ICM4_THEAB) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site381Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2551Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1321Substrate By similarity HAMAP-Rule MF_01201
Binding site3031Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue381N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
B7ICM4 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 6C17BA6F3E725F2C

FASTA36440,923
        10         20         30         40         50         60 
MGTESRRTFA EININNYIEN LKYFQKKCSP AKVMPVIKAN AYGHGAVMLA KSAEKMGIDY 

        70         80         90        100        110        120 
FAVAFLEEAL ILRKNGINTN ILVFNYLDKD FVPLAADNNI TITIISNEQV EEYKDLIKKP 

       130        140        150        160        170        180 
KVHINIDTGM NRVGIEPKDA MKIYEKLISN GFEVEGIYTH FAVADSLKKE DIEFTKKQYE 

       190        200        210        220        230        240 
KFLEVNLPVK IRHTNNSAAS LSGIISCGDY VRIGIASYGL MPSNQVKDEN LKPVLTWKSV 

       250        260        270        280        290        300 
VSHVKTLKKG ESVSYGRTFV APYDMKVATI PVGYADGYWR HLSNNGEVLI NGKRRKILGR 

       310        320        330        340        350        360 
VCMDQFVVEA DDEVKIGDEV ILIGKQGNEF ISAEEIADKV GTINYEVTCR ISERVPRIYK 


GVEL 

« Hide

References

[1]"The genome of Thermosipho africanus TCF52B: lateral genetic connections to the Firmicutes and Archaea."
Nesbo C.L., Bapteste E., Curtis B., Dahle H., Lopez P., Macleod D., Dlutek M., Bowman S., Zhaxybayeva O., Birkeland N.K., Doolittle W.F.
J. Bacteriol. 191:1974-1978(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TCF52B EMBL ACJ75751.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001185 Genomic DNA. Translation: ACJ75751.1.
RefSeqYP_002335092.1. NC_011653.1.

3D structure databases

ProteinModelPortalB7ICM4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING484019.THA_1306.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACJ75751; ACJ75751; THA_1306.
GeneID7071972.
KEGGtaf:THA_1306.
PATRIC23919629. VBITheAfr129358_1318.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAAEININN.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycTAFR484019:GJOH-1340-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB7ICM4_THEAB
AccessionPrimary (citable) accession number: B7ICM4
Entry history
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: July 9, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)