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Protein

60 kDa chaperonin

Gene

groL

Organism
Acinetobacter baumannii (strain AB0057)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:AB57_3079
OrganismiAcinetobacter baumannii (strain AB0057)
Taxonomic identifieri480119 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001299571 – 54460 kDa chaperoninAdd BLAST544

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB7I618.
SMRiB7I618.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

B7I618-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAKDVKFGD SARSKMIAGV NVLADAVKVT LGPKGRNVVI DRSFGAPHIT
60 70 80 90 100
KDGVTVAKEI SLKDKFENMG AQLVREVSSK TNDIAGDGTT TATVLAQAIL
110 120 130 140 150
NEGIKSVTAG MNPMDLKRGI DIAVKTVVEN IRSIAKPADD FKAIEQVGSI
160 170 180 190 200
SANSDTTVGK LIAQAMEKVG KEGVITVEEG SGFEDALDVV EGMQFDRGYI
210 220 230 240 250
SPYFANKQDT LTAELENPFI LLVDKKISNI RELISVLEAV AKTGKPLLII
260 270 280 290 300
AEDVEGEALA TLVVNNMRGI IKVCAVKAPG FGDRRKAMLQ DIAILTGATV
310 320 330 340 350
ISEEVGMSLE QATLQDLGTA HKITVSKENT VIVDGAGDAA AIAERVQQIR
360 370 380 390 400
AQIEESTSEY DREKLQERVA KLAGGVAVIK IGAATEVEMK EKKDRVDDAL
410 420 430 440 450
HATRAAVEEG VVAGGGVALV RAVNALEGLK GANEDQTAGI NILRRAIEAP
460 470 480 490 500
LRQIVANAGD EPSVVINAVK NGEGNFGYNA ATGEYGDMLE MGILDPAKVT
510 520 530 540
RSALEHAASV AGLMLTTECM ITDIPEDKPA APDMGGMGGM GGMM
Length:544
Mass (Da):57,166
Last modified:February 10, 2009 - v1
Checksum:i59547DF028D633D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001182 Genomic DNA. Translation: ACJ42411.1.
RefSeqiWP_001274623.1. NC_011586.1.

Genome annotation databases

EnsemblBacteriaiACJ42411; ACJ42411; AB57_3079.
GeneIDi31348953.
KEGGiabn:AB57_3079.

Similar proteinsi

Entry informationi

Entry nameiCH60_ACIB5
AccessioniPrimary (citable) accession number: B7I618
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: June 7, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families