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Protein

ATP-dependent Clp protease ATP-binding subunit ClpX

Gene

clpX

Organism
Acinetobacter baumannii (strain AB0057)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri11 – 36C4-typeUniRule annotationAdd BLAST26
Nucleotide bindingi119 – 126ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent Clp protease ATP-binding subunit ClpXUniRule annotation
Gene namesi
Name:clpXUniRule annotation
Ordered Locus Names:AB57_0581
OrganismiAcinetobacter baumannii (strain AB0057)
Taxonomic identifieri480119 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001896741 – 437ATP-dependent Clp protease ATP-binding subunit ClpXAdd BLAST437

Interactioni

Subunit structurei

Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.UniRule annotation

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB7I5E4.
SMRiB7I5E4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ClpX chaperone family.UniRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri11 – 36C4-typeUniRule annotationAdd BLAST26

Keywords - Domaini

Zinc-finger

Phylogenomic databases

HOGENOMiHOG000010093.
KOiK03544.
OMAiDIMYDLP.

Family and domain databases

HAMAPiMF_00175. ClpX. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR004487. Clp_protease_ATP-bd_su_ClpX.
IPR027417. P-loop_NTPase.
IPR010603. Znf_CppX_C4.
PANTHERiPTHR11262. PTHR11262. 2 hits.
PfamiView protein in Pfam
PF07724. AAA_2. 1 hit.
PF10431. ClpB_D2-small. 1 hit.
PF06689. zf-C4_ClpX. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM01086. ClpB_D2-small. 1 hit.
SM00994. zf-C4_ClpX. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00382. clpX. 1 hit.

Sequencei

Sequence statusi: Complete.

B7I5E4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEHPQGQKH CSFCGKTQSE VGKLIAGEDA YICNECVDVC LDLVQTSQQV
60 70 80 90 100
EAGDWASKAL PKPHEIRAAL DQYVIGQDLA KKTLSVAVYN HYKRLKVGQS
110 120 130 140 150
GHVSKDVEIA KSNILLIGPT GSGKTLLAQT LARLLDVPFA MADATTLTEA
160 170 180 190 200
GYVGEDVENI VQKLLQKADY DVEKAQKGII YIDEIDKITR KSENPSITRD
210 220 230 240 250
VSGEGVQQAL LKMIEGTVAS IPPQGGRKHP QQEFIQIDTS NILFICGGAF
260 270 280 290 300
AGLEKIVQQR QEKGGIGFTA DVKNKDETKK LAELFRQVEP TDLVKFGLIP
310 320 330 340 350
EFIGRLPVIA TLEELDEEAL MQILTEPKNA LTRQYQYLFN MENVDLVFED
360 370 380 390 400
SALRAVAKRA LERNTGARGL RSILENVLLE TMYDLPSRTD VGTVFINEAV
410 420 430
INGEAEPVYK SERQPKEAVT HESVAKADLK VIDSKSA
Length:437
Mass (Da):48,083
Last modified:February 10, 2009 - v1
Checksum:i3A78784709BB089D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001182 Genomic DNA. Translation: ACJ40002.1.

Genome annotation databases

EnsemblBacteriaiACJ40002; ACJ40002; AB57_0581.
KEGGiabn:AB57_0581.

Similar proteinsi

Entry informationi

Entry nameiCLPX_ACIB5
AccessioniPrimary (citable) accession number: B7I5E4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: October 25, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families