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B7I5C6

- PUR5_ACIB5

UniProt

B7I5C6 - PUR5_ACIB5

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene
purM, AB57_3014
Organism
Acinetobacter baumannii (strain AB0057)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciABAU480119:GHQY-2999-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:AB57_3014
OrganismiAcinetobacter baumannii (strain AB0057)
Taxonomic identifieri480119 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
ProteomesiUP000007094: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 356356Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotationPRO_1000192981Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi480119.AB57_3014.

Structurei

3D structure databases

ProteinModelPortaliB7I5C6.
SMRiB7I5C6. Positions 10-356.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiVIGKIEH.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

B7I5C6-1 [UniParc]FASTAAdd to Basket

« Hide

MSNSTSTPNT GLSYKDAGVD IEAGDALVDR IKSVAKRTTR PEVMGGLGGF    50
GALCKIPKGY EEPVLVSGTD GVGTKLRLAL NLNRHDTIGQ DLVAMCVNDL 100
LVCGAEPLFF LDYYATGHLN VDVAANVVTG IGKGCELAGC ALVGGETAEM 150
PGMYEGEDYD LAGFAVGVVE QSKIIDGSKV KSGDVLIGVA SSGAHSNGYS 200
LLRKILDVKN VDLTQVIDGR PLADVAMEPT RIYVKPVLEL CKQVDVHAMA 250
HITGGGLPGN LPRVLPNGAQ AVINEASWEW PELFKLLQRE GNVERFEMYR 300
TFNCGVGMVI AVDANDAEKA IEVLNAQGEK AWKIGHIQEN AESVEGADEK 350
IRVIFE 356
Length:356
Mass (Da):37,875
Last modified:February 10, 2009 - v1
Checksum:i9C790D38127F3C41
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001182 Genomic DNA. Translation: ACJ42353.1.
RefSeqiYP_002320342.1. NC_011586.1.

Genome annotation databases

EnsemblBacteriaiACJ42353; ACJ42353; AB57_3014.
GeneIDi7046480.
KEGGiabn:AB57_3014.
PATRICi20699721. VBIAciBau111166_2909.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001182 Genomic DNA. Translation: ACJ42353.1 .
RefSeqi YP_002320342.1. NC_011586.1.

3D structure databases

ProteinModelPortali B7I5C6.
SMRi B7I5C6. Positions 10-356.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 480119.AB57_3014.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACJ42353 ; ACJ42353 ; AB57_3014 .
GeneIDi 7046480.
KEGGi abn:AB57_3014.
PATRICi 20699721. VBIAciBau111166_2909.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi VIGKIEH.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci ABAU480119:GHQY-2999-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AB0057.

Entry informationi

Entry nameiPUR5_ACIB5
AccessioniPrimary (citable) accession number: B7I5C6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: May 14, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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