B7I530 (KCY_ACIB5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	AB57_1816

Organism

Acinetobacter baumannii (strain AB0057) [Complete proteome] [HAMAP]

Taxonomic identifier

480119 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter › Acinetobacter calcoaceticus/baumannii complex

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 228	228	Cytidylate kinase HAMAP MF_00238		PRO_1000119002
Regions
	Nucleotide binding	10 – 18	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	B7I530 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 1ED7ED172328DF77	FASTA	228	25,238
	10 20 30 40 50 60 MTVQIITIDG PSGSGKGTLA AKLAAYYQFH LLDSGALYRL LGLSLHKHDL LEKLDSHLDM 70 80 90 100 110 120 CVNYARQLNI KFETSAEGTL VFLDGEDVTQ TIRTERVGEY ASKVAAIPEL RQALFERQRA 130 140 150 160 170 180 FAQTPGLVAD GRDMATSIFP EANAKIYLTA SAESRAERRV KQLQGMGLDA KINDILANIQ 190 200 210 220 ARDKRDMERE VAPLKPAADA YIIDSSELTI DQVFKLMVDY VNSRTVSN

References

[1]

"Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii." Adams M.D., Goglin K., Molyneaux N., Hujer K.M., Lavender H., Jamison J.J., MacDonald I.J., Martin K.M., Russo T., Campagnari A.A., Hujer A.M., Bonomo R.A., Gill S.R. J. Bacteriol. 190:8053-8064(2008) [PubMed: 18931120] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AB0057.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001182 Genomic DNA. Translation: ACJ41195.1.
RefSeq	YP_002319178.1. NC_011586.1.
3D structure databases
ProteinModelPortal	B7I530.
ModBase	Search...
Protein-protein interaction databases
STRING	B7I530.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7044897.
GenomeReviews	Gene locus AB57_1816 in contig CP001182_GR.
KEGG	abn:AB57_1816.
PATRIC	20697412. VBIAciBau111166_1767.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG354377.
OMA	DIGTVIC.
ProtClustDB	PRK00023.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_ACIB5

Accession

Primary (citable) accession number: B7I530

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program