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B7I441

- TRPC_ACIB5

UniProt

B7I441 - TRPC_ACIB5

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Protein
Indole-3-glycerol phosphate synthase
Gene
trpC, AB57_2790
Organism
Acinetobacter baumannii (strain AB0057)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. indole-3-glycerol-phosphate synthase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciABAU480119:GHQY-2781-MONOMER.
UniPathwayiUPA00035; UER00043.

Names & Taxonomyi

Protein namesi
Recommended name:
Indole-3-glycerol phosphate synthase (EC:4.1.1.48)
Short name:
IGPS
Gene namesi
Name:trpC
Ordered Locus Names:AB57_2790
OrganismiAcinetobacter baumannii (strain AB0057)
Taxonomic identifieri480119 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex
ProteomesiUP000007094: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 268268Indole-3-glycerol phosphate synthaseUniRule annotation
PRO_1000117766Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi480119.AB57_2790.

Structurei

3D structure databases

ProteinModelPortaliB7I441.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpC family.

Phylogenomic databases

eggNOGiCOG0134.
HOGENOMiHOG000230463.
KOiK01609.
OMAiTPYQVWE.
OrthoDBiEOG6WT8JX.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00134_B. IGPS_B.
InterProiIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
PROSITEiPS00614. IGPS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7I441-1 [UniParc]FASTAAdd to Basket

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MINIQNTILG KIVDRKHEEL AARLKQRNLQ DVEELAKAAT PVRGFANALQ    50
HKRPGVIAEI KKASPSKGII RADFNPAEIA QQYEQAGAAC LSVLTDVDFF 100
QGADENIAIA RNHCALPALR KDFLVDPYNV VEARALHADC ILLIVACLSD 150
QQLEEMSKTA FEHQLDVLVE VHDEEELERA LKLSEQCLLG VNNRNLKTFD 200
VDLNTTIRLK KLLPASRLLI TESGIATPDD VRMMQEHDIH SFLVGESFMK 250
QPRPDQAFTA LFGQPQTV 268
Length:268
Mass (Da):29,911
Last modified:February 10, 2009 - v1
Checksum:i707CD7187208D29B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001182 Genomic DNA. Translation: ACJ42140.1.
RefSeqiYP_002320129.1. NC_011586.1.

Genome annotation databases

EnsemblBacteriaiACJ42140; ACJ42140; AB57_2790.
GeneIDi7046917.
KEGGiabn:AB57_2790.
PATRICi20699279. VBIAciBau111166_2691.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001182 Genomic DNA. Translation: ACJ42140.1 .
RefSeqi YP_002320129.1. NC_011586.1.

3D structure databases

ProteinModelPortali B7I441.
ModBasei Search...

Protein-protein interaction databases

STRINGi 480119.AB57_2790.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACJ42140 ; ACJ42140 ; AB57_2790 .
GeneIDi 7046917.
KEGGi abn:AB57_2790.
PATRICi 20699279. VBIAciBau111166_2691.

Phylogenomic databases

eggNOGi COG0134.
HOGENOMi HOG000230463.
KOi K01609.
OMAi TPYQVWE.
OrthoDBi EOG6WT8JX.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00043 .
BioCyci ABAU480119:GHQY-2781-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00134_B. IGPS_B.
InterProi IPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00218. IGPS. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
PROSITEi PS00614. IGPS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AB0057.

Entry informationi

Entry nameiTRPC_ACIB5
AccessioniPrimary (citable) accession number: B7I441
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: May 14, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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