Reviewed, UniProtKB/Swiss-Prot B7I242 (PSD_ACIB5)

Names and origin

Protein names

Recommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	AB57_3830

Organism

Acinetobacter baumannii (strain AB0057) [Complete proteome] [HAMAP]

Taxonomic identifier

480119 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	283 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662
Cofactor	Pyruvoyl group By similarity.
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phospholipid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 249	249	Phosphatidylserine decarboxylase beta chain By similarity		PRO_1000131318
	Chain	250 – 283	34	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_1000131319
Sites
	Site	249 – 250	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	250	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	B7I242-1 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 16EA3442F9CF7230	FASTA	283	31,272
	10 20 30 40 50 60 MSFTSRLKKE LFIKAQNLVP QHQLSRVVGK VAASENPILK AAVIHAFKTK YGIDLSIAEQ 70 80 90 100 110 120 GNALKYKSFN DFFTRALKDG VRLVDENPDS IVSPADGAIS QIGKITAGEV FQAKGQSFSV 130 140 150 160 170 180 EKLIGDPQLA QPFQEGEFAT VYLSPRDYHR VHMPFSGTLT ETLYVPGELF SVNQVTAENV 190 200 210 220 230 240 PGLFARNERM VCLFDTELGR MAVVLVGAMI VAGIETVATG KVKPSGRIEL QHHELKLEKG 250 260 270 280 AELGRFYLGS TAIILFEKDK IEWEKRFKAE SVVVMGERMG HTL

References

[1]

"Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii." Adams M.D., Goglin K., Molyneaux N., Hujer K.M., Lavender H., Jamison J.J., MacDonald I.J., Martin K.M., Russo T., Campagnari A.A., Hujer A.M., Bonomo R.A., Gill S.R. J. Bacteriol. 190:8053-8064(2008) [PubMed: 18931120] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001182 Genomic DNA. Translation: ACJ43182.1.
RefSeq	YP_002321118.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	7045264.
GenomeReviews	Gene locus AB57_3830 in contig CP001182_GR.
KEGG	abn:AB57_3830.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_00662. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR005221. PS_decarb. [Graphical view]
PANTHER	PTHR10067. PS_decarb. 1 hit.
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00163. PS_decarb. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_ACIB5

Accession

Primary (citable) accession number: B7I242

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	June 16, 2009
This is version 6 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)