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B7I1Q9 (DADA_ACIB5) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
D-amino acid dehydrogenase small subunit

EC=1.4.99.1
Gene names
Name:dadA
Ordered Locus Names:AB57_0138
OrganismAcinetobacter baumannii (strain AB0057) [Complete proteome] [HAMAP]
Taxonomic identifier480119 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex

Protein attributes

Sequence length421 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Oxidative deamination of D-amino acids By similarity. HAMAP-Rule MF_01202

Catalytic activity

A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP-Rule MF_01202

Cofactor

FAD By similarity. HAMAP-Rule MF_01202

Pathway

Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP-Rule MF_01202

Subunit structure

Heterodimer of a small and a large subunit By similarity.

Sequence similarities

Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-alanine catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionD-amino-acid dehydrogenase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 421421D-amino acid dehydrogenase small subunit HAMAP-Rule MF_01202
PRO_1000138635

Regions

Nucleotide binding3 – 1715FAD Potential

Sequences

Sequence LengthMass (Da)Tools
B7I1Q9 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: D0449A9235CA9AA5

FASTA42146,426
        10         20         30         40         50         60 
MRVIVLGSGV IGVASAYYLA RQGAEVTVLD RQSGPAEETS FGNAGQISPG YSTPWAAPGI 

        70         80         90        100        110        120 
PFKAVKWMFQ HHAPLAINLD GSMWQLQWMA QMLKNCNPQS YAVNKERMMR VAEYSRDCLR 

       130        140        150        160        170        180 
ELRKDTGIHY ENRAKGTLQL FRKEAQMEAV QRDISVLEEC GVSYELLNGN ELGRVEPALA 

       190        200        210        220        230        240 
NAQDKLVGGL HLPNDETGDC YLFTNALAQI AKELGVNFQF NQNVEKLIVE GDQIKGVQVN 

       250        260        270        280        290        300 
GKVLTADRYV LAFGSYSRDF LKPLDLQLPV YPVKGYSLTI PIVDPAFAPQ STVLDETYKI 

       310        320        330        340        350        360 
AITRFDQRIR VGGMAELSGF NLGLNEDRRA TLQMVTQDLF PGGDMAQASF WTGLRPMTPD 

       370        380        390        400        410        420 
STPIIGATRF KNLFLNTGHG TLGWTMACGS GKLISDIVLN HKTDISTDGL SIQRYSHAHA 


A 

« Hide

References

[1]"Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii."
Adams M.D., Goglin K., Molyneaux N., Hujer K.M., Lavender H., Jamison J.J., MacDonald I.J., Martin K.M., Russo T., Campagnari A.A., Hujer A.M., Bonomo R.A., Gill S.R.
J. Bacteriol. 190:8053-8064(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AB0057.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001182 Genomic DNA. Translation: ACJ39569.1.
RefSeqYP_002317552.1. NC_011586.1.

3D structure databases

ProteinModelPortalB7I1Q9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING480119.AB57_0138.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACJ39569; ACJ39569; AB57_0138.
GeneID7044402.
KEGGabn:AB57_0138.
PATRIC20694083. VBIAciBau111166_0142.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0665.
HOGENOMHOG000217450.
KOK00285.
OMANDLYPRG.
OrthoDBEOG6KMBD9.
ProtClustDBPRK00711.

Enzyme and pathway databases

BioCycABAU480119:GHQY-142-MONOMER.
UniPathwayUPA00043; UER00498.

Family and domain databases

HAMAPMF_01202. DadA.
InterProIPR023080. D-aa_DH_ssu_DadA.
IPR006076. FAD-dep_OxRdtase.
[Graphical view]
PfamPF01266. DAO. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDADA_ACIB5
AccessionPrimary (citable) accession number: B7I1Q9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: February 19, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways