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B7HZJ9 (B7HZJ9_BACC7) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase 1 HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase 1 HAMAP MF_00323
Protoheme ferro-lyase 1 HAMAP MF_00323
Gene names
Name:hemH1 HAMAP MF_00323 EMBL ACJ79660.1
Ordered Locus Names:BCAH187_A1231
OrganismBacillus cereus (strain AH187) [Complete proteome] [HAMAP]
Taxonomic identifier405534 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length311 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1821Iron By similarity HAMAP MF_00323
Metal binding2631Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
B7HZJ9 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: C82AA074CBB28A1B

FASTA31135,261
        10         20         30         40         50         60 
MKKKIGLLVM AYGTPYKEED IERYYTHIRR GRKPSPEMLE DLTERYRAIG GISPLATITL 

        70         80         90        100        110        120 
EQAKKLEKRL NEVQDEVEYH MYLGLKHIEP FIEDAVKDMH NDGIQDAIAL VLAPHYSTFS 

       130        140        150        160        170        180 
VKSYVGRAQE EAEKLGNLTI HGIDSWYKEP KFIQYWVDAV KGIYSGMSDA EREKAVLIVS 

       190        200        210        220        230        240 
AHSLPEKIIA MGDPYPDQLN ETADYIARGA EVANYAVGWQ SAGNTPDPWI GPDVQDLTRE 

       250        260        270        280        290        300 
LNEKHGYTSF VYAPVGFVAE HLEVLYDNDF ECKVVTDEIG AKYYRPEMPN ASDAFIDCLT 

       310 
DVVVKKKESV L

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References

[1]"Genome sequence of Bacillus cereus AH187."
Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Kolsto A.B., Okstad O.A., Ravel J., Sutton G.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001177 Genomic DNA. Translation: ACJ79660.1.
RefSeqYP_002337201.1. NC_011658.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB7HZJ9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000094368; EBBACP00000091978; EBBACG00000094361.
GeneID7075699.
GenomeReviewsGene locus BCAH187_A1231 in contig CP001177_GR.
KEGGbcr:BCAH187_A1231.
PATRIC18827879. VBIBacCer120511_1414.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000002085.
HOGENOMHBG697135.
OMACSETIFE.
ProtClustDBPRK12435.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB7HZJ9_BACC7
AccessionPrimary (citable) accession number: B7HZJ9
Entry history
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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