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Protein

60 kDa chaperonin

Gene

groL

Organism
Bacillus cereus (strain AH187)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:BCAH187_A0317
OrganismiBacillus cereus (strain AH187)
Taxonomic identifieri405534 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000002214 Componenti: Chromosome

Subcellular locationi

B7HS05:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001299741 – 54460 kDa chaperoninAdd BLAST544

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB7HS05.
SMRiB7HS05.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

B7HS05-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKDIKFSEE ARRSMLRGVD TLANAVKVTL GPKGRNVVLE KKFGSPLITN
60 70 80 90 100
DGVTIAKEIE LEDAFENMGA KLVAEVASKT NDVAGDGTTT ATVLAQAMIR
110 120 130 140 150
EGLKNVTAGA NPMGLRKGIE KAVVAAVEEL KTISKPIEGK SSIAQVAAIS
160 170 180 190 200
AADEEVGQLI AEAMERVGND GVITLEESKG FTTELDVVEG MQFDRGYASP
210 220 230 240 250
YMITDSDKME AVLDNPYILI TDKKISNIQE ILPVLEQVVQ QGKPLLIIAE
260 270 280 290 300
DVEGEALATL VVNKLRGTFN VVAVKAPGFG DRRKAMLEDI AILTGGEVIT
310 320 330 340 350
EELGRDLKSA TVESLGRAGK VVVTKENTTV VEGVGSTEQI EARIGQIRAQ
360 370 380 390 400
LEETTSEFDR EKLQERLAKL AGGVAVIKVG AATETELKER KLRIEDALNS
410 420 430 440 450
TRAAVEEGIV AGGGTSLMNV YTKVASIVAE GDEATGINIV LRALEEPVRQ
460 470 480 490 500
IAINAGLEGS VVVERLKGEK VGVGFNAATG EWVNMLETGI VDPAKVTRSA
510 520 530 540
LQNAASVAAM FLTTEAVVAD KPEPNAPAMP DMGGMGMGGM GGMM
Length:544
Mass (Da):57,404
Last modified:February 10, 2009 - v1
Checksum:i47F42CF7A4FA804E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001177 Genomic DNA. Translation: ACJ79330.1.
RefSeqiWP_001029999.1. NC_011658.1.

Genome annotation databases

EnsemblBacteriaiACJ79330; ACJ79330; BCAH187_A0317.
KEGGibcr:BCAH187_A0317.

Similar proteinsi

Entry informationi

Entry nameiCH60_BACC7
AccessioniPrimary (citable) accession number: B7HS05
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: October 25, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families