Reviewed, UniProtKB/Swiss-Prot B7HPN7 (PSD_BACC7)

Names and origin

Protein names

Recommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	BCAH187_A4471

Organism

Bacillus cereus (strain AH187) [Complete proteome] [HAMAP]

Taxonomic identifier

405534 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	262 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662
Cofactor	Pyruvoyl group By similarity. HAMAP MF_00662
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phospholipid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 225	225	Phosphatidylserine decarboxylase beta chain By similarity		PRO_1000131346
	Chain	226 – 262	37	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_1000131347
Sites
	Site	225 – 226	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	226	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	B7HPN7-1 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 3EB7AA85B57BA91B	FASTA	262	29,918
	10 20 30 40 50 60 MRRTLYRLMI ELTNGRFTSY ILRKFAQSRL SSIIIPSYAK VFQINQDEME KGLKEYRTLH 70 80 90 100 110 120 ELFTRKLKEG KRSIDTDASS IVSPVDGVFA DHGPIEDTKT FDIKGKRYSI VDMLGNEERA 130 140 150 160 170 180 QRYAGGTYMV IYLSPSHYHR IHSPLSGSVT ERFVLGRKSY PVNAAGMEYG KEPLSKNYRS 190 200 210 220 230 240 VTEVNSDGEH MALVKVGAMF VNSIELLHER DTVQKGEEMA YFTFGSTVVL LFEKDMIEVV 250 260 QELKSGQELR LGEKIATRLA HK

References

[1]	"Genome sequence of Bacillus cereus AH187." Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Kolsto A.B., Okstad O.A., Ravel J., Sutton G. Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001177 Genomic DNA. Translation: ACJ81767.1.
RefSeq	YP_002340398.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	7074258.
GenomeReviews	Gene locus BCAH187_A4471 in contig CP001177_GR.
KEGG	bcr:BCAH187_A4471.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG302256.
OMA	ALFSVNP.
Family and domain databases
HAMAP	MF_00662. PS_decarb_type1. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR005221. PS_decarb. [Graphical view]
PANTHER	PTHR10067. PS_decarb. 1 hit.
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00163. PS_decarb. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_BACC7

Accession

Primary (citable) accession number: B7HPN7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	February 9, 2010
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)