Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B7HP06

- B7HP06_BACC7

UniProt

B7HP06 - B7HP06_BACC7

Protein

Alanine racemase

Gene

dal2

Organism
Bacillus cereus (strain AH187)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (10 Feb 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei41 – 411Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei139 – 1391SubstrateUniRule annotation
    Active sitei269 – 2691Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei317 – 3171Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciBCER405534:GHXM-2131-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:dal2Imported
    Ordered Locus Names:BCAH187_A2178Imported
    OrganismiBacillus cereus (strain AH187)Imported
    Taxonomic identifieri405534 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000002214: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei41 – 411N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi405534.BCAH187_A2178.

    Structurei

    3D structure databases

    ProteinModelPortaliB7HP06.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiLWQLEAI.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B7HP06-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLKYGRDTI VEVDLNAVKH NVKEFKKRVN DENIAMMAAV KANGYGHGAV    50
    EVAKAAIEAG INQLAVAFVD EAIELREAGI NVPILILGYT SVASAEEAIQ 100
    YDVMMTVYRS EDLQGINEIA NRLQKKAQIQ VKIDTGMSRI GLQEEEVKPF 150
    LEELKRMEYV EVVGMFTHYS TADEIDKSYT NMQTSLFEKA VNTAKELGIH 200
    IPYIHSSNSA GSMELSNTFQ NMVRVGIGIY GMYPSKEVDH SVVSLQPALS 250
    LKSKVAHIKH AKKNRGVSYG NTYVTTGEEW IATIPIGYAD GYNRQLSNKG 300
    HALINGVRVP VIGRVCMDQL MLDVSKAMPV QVGDEVVFYG KQGEENIAVE 350
    EIADMLGTIN YEVTCMLDRR IPRVYKENNE TTAIVNILRK N 391
    Length:391
    Mass (Da):43,419
    Last modified:February 10, 2009 - v1
    Checksum:iF4C5F7D26308FB83
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001177 Genomic DNA. Translation: ACJ79834.1.
    RefSeqiYP_002338131.1. NC_011658.1.

    Genome annotation databases

    EnsemblBacteriaiACJ79834; ACJ79834; BCAH187_A2178.
    GeneIDi7073019.
    KEGGibcr:BCAH187_A2178.
    PATRICi18829756. VBIBacCer120511_2351.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001177 Genomic DNA. Translation: ACJ79834.1 .
    RefSeqi YP_002338131.1. NC_011658.1.

    3D structure databases

    ProteinModelPortali B7HP06.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 405534.BCAH187_A2178.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACJ79834 ; ACJ79834 ; BCAH187_A2178 .
    GeneIDi 7073019.
    KEGGi bcr:BCAH187_A2178.
    PATRICi 18829756. VBIBacCer120511_2351.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi LWQLEAI.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci BCER405534:GHXM-2131-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Bacillus cereus AH187."
      Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Kolsto A.B., Okstad O.A., Ravel J., Sutton G.
      Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AH187Imported.

    Entry informationi

    Entry nameiB7HP06_BACC7
    AccessioniPrimary (citable) accession number: B7HP06
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 10, 2009
    Last sequence update: February 10, 2009
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3