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B7HP06 (B7HP06_BACC7) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201 RuleBase RU004247

EC=5.1.1.1 HAMAP-Rule MF_01201 RuleBase RU004247
Gene names
Name:dal2 EMBL ACJ79834.1
Ordered Locus Names:BCAH187_A2178 EMBL ACJ79834.1
OrganismBacillus cereus (strain AH187) [Complete proteome] [HAMAP] EMBL ACJ79834.1
Taxonomic identifier405534 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site411Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2691Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1391Substrate By similarity HAMAP-Rule MF_01201
Binding site3171Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue411N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
B7HP06 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: F4C5F7D26308FB83

FASTA39143,419
        10         20         30         40         50         60 
MSLKYGRDTI VEVDLNAVKH NVKEFKKRVN DENIAMMAAV KANGYGHGAV EVAKAAIEAG 

        70         80         90        100        110        120 
INQLAVAFVD EAIELREAGI NVPILILGYT SVASAEEAIQ YDVMMTVYRS EDLQGINEIA 

       130        140        150        160        170        180 
NRLQKKAQIQ VKIDTGMSRI GLQEEEVKPF LEELKRMEYV EVVGMFTHYS TADEIDKSYT 

       190        200        210        220        230        240 
NMQTSLFEKA VNTAKELGIH IPYIHSSNSA GSMELSNTFQ NMVRVGIGIY GMYPSKEVDH 

       250        260        270        280        290        300 
SVVSLQPALS LKSKVAHIKH AKKNRGVSYG NTYVTTGEEW IATIPIGYAD GYNRQLSNKG 

       310        320        330        340        350        360 
HALINGVRVP VIGRVCMDQL MLDVSKAMPV QVGDEVVFYG KQGEENIAVE EIADMLGTIN 

       370        380        390 
YEVTCMLDRR IPRVYKENNE TTAIVNILRK N 

« Hide

References

[1]"Genome sequence of Bacillus cereus AH187."
Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Kolsto A.B., Okstad O.A., Ravel J., Sutton G.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AH187 EMBL ACJ79834.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001177 Genomic DNA. Translation: ACJ79834.1.
RefSeqYP_002338131.1. NC_011658.1.

3D structure databases

ProteinModelPortalB7HP06.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING405534.BCAH187_A2178.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACJ79834; ACJ79834; BCAH187_A2178.
GeneID7073019.
KEGGbcr:BCAH187_A2178.
PATRIC18829756. VBIBacCer120511_2351.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMALWQLEAI.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycBCER405534:GHXM-2131-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB7HP06_BACC7
AccessionPrimary (citable) accession number: B7HP06
Entry history
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: July 9, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)