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B7HMQ9 (DEOC_BACC7) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Deoxyribose-phosphate aldolase
Short name=DERA
EC=4.1.2.4
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase
Phosphodeoxyriboaldolase
Short name=Deoxyriboaldolase
Gene names
Name:deoC
Ordered Locus Names:BCAH187_A2002
OrganismBacillus cereus (strain AH187) [Complete proteome] [HAMAP]
Taxonomic identifier405534 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length223 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114

Subcellular location

Cytoplasm By similarity HAMAP MF_00114.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processdeoxyribonucleotide catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondeoxyribose-phosphate aldolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 223223Deoxyribose-phosphate aldolase HAMAP MF_00114
PRO_1000117542

Sites

Active site1521Schiff-base intermediate with acetaldehyde By similarity
Active site1811 By similarity

Sequences

Sequence LengthMass (Da)Tools
B7HMQ9 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: DED7BF14538A1029

FASTA22323,440
        10         20         30         40         50         60 
MNIAKLIDHT ILKANATKED VMKVIEEAKE YKFASVCINP TWVKLAAEEL AGHDVDVCTV 

        70         80         90        100        110        120 
IGFPLGASTT ETKAFETKDA IAKGATEVDM VINVGALKDG DDELVEKDIY EVVQAAKGKA 

       130        140        150        160        170        180 
LVKVIIETCL LTDEEKVRAC ELSVKAGADF VKTSTGFSTG GATAEDIALM RKTVGPNVGV 

       190        200        210        220 
KASGGVRTRE DADKMVAAGA SRIGASASVA IVLNDAKDAT DNY

« Hide

References

[1]"Genome sequence of Bacillus cereus AH187."
Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Kolsto A.B., Okstad O.A., Ravel J., Sutton G.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AH187.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001177 Genomic DNA. Translation: ACJ77898.1.
RefSeqYP_002337955.1. NC_011658.1.

3D structure databases

ProteinModelPortalB7HMQ9.
ModBaseSearch...

Protein-protein interaction databases

STRINGB7HMQ9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000092833; EBBACP00000090132; EBBACG00000092826.
GeneID7078029.
GenomeReviewsGene locus BCAH187_A2002 in contig CP001177_GR.
KEGGbcr:BCAH187_A2002.
PATRIC18829403. VBIBacCer120511_2175.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000000908.
HOGENOMHBG636421.
OMACLEAREN.
ProtClustDBPRK00507.

Family and domain databases

HAMAPMF_00114. DeoC_type1.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/AroFGH_arch.
IPR022979. Deoxyribose_phosphate_aldo_1.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01619.
PANTHERPTHR10889. DeoC. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. DeoC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDEOC_BACC7
AccessionPrimary (citable) accession number: B7HMQ9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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