B7HMM2 (B7HMM2_BACC7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA1 EMBL ACJ81125.1
Synonyms:	msrA HAMAP MF_01401
Ordered Locus Names:	BCAH187_A1964

Organism

Bacillus cereus (strain AH187) [Complete proteome] [HAMAP]

Taxonomic identifier

405534 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569 EMBL ACJ81125.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	15	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	B7HMM2 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: F690BD64CFFBAC06	FASTA	178	20,522
	10 20 30 40 50 60 MSEKTYELAT FAGGCFWCMV KPFDELPGIH KVLSGYAGGH VENPTYEQVK AGTSGHLEVV 70 80 90 100 110 120 QITFDPSIFP YEKLLDLYWP QIDPTDDGGQ FFDRGPSYRT AIFYHTETQK ELAEKSKQTL 130 140 150 160 170 AESGMFKEPI VTEIRPAAPF YEAEEYHQHF YKKNPEKYAT EQKESGRADF IKENWQKK

References

[1]	"Genome sequence of Bacillus cereus AH187." Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Kolsto A.B., Okstad O.A., Ravel J., Sutton G. Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001177 Genomic DNA. Translation: ACJ81125.1.
RefSeq	YP_002337918.1. NC_011658.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B7HMM2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000090678; EBBACP00000092022; EBBACG00000090671.
GeneID	7075061.
GenomeReviews	Gene locus BCAH187_A1964 in contig CP001177_GR.
KEGG	bcr:BCAH187_A1964.
PATRIC	18829323. VBIBacCer120511_2135.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000000580.
HOGENOM	HBG748152.
OMA	LVELYWT.
ProtClustDB	CLSK916383.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B7HMM2_BACC7

Accession

Primary (citable) accession number: B7HMM2

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)