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B7HIT0 (DEOC_BACC4) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Deoxyribose-phosphate aldolase
Short name=DERA
EC=4.1.2.4
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase
Phosphodeoxyriboaldolase
Short name=Deoxyriboaldolase
Gene names
Name:deoC
Ordered Locus Names:BCB4264_A1895
OrganismBacillus cereus (strain B4264) [Complete proteome] [HAMAP]
Taxonomic identifier405532 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length223 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114

Subcellular location

Cytoplasm By similarity HAMAP MF_00114.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processdeoxyribonucleotide catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondeoxyribose-phosphate aldolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 223223Deoxyribose-phosphate aldolase HAMAP MF_00114
PRO_1000117541

Sites

Active site1521Schiff-base intermediate with acetaldehyde By similarity
Active site1811 By similarity

Sequences

Sequence LengthMass (Da)Tools
B7HIT0 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 74D6274A254628F1

FASTA22323,369
        10         20         30         40         50         60 
MNIAKLIDHT ILKANSTKED VMKVIEEAKE YKFASVCINP TWVKLAADEL AGHDVDVCTV 

        70         80         90        100        110        120 
IGFPLGASTT ETKAFETKDA IAKGATEVDM VINVGALKDG DNELVEKDIY EVVQAAKGKA 

       130        140        150        160        170        180 
LVKVIIETCL LTDEEKVRAC ELSVKAGADF VKTSTGFSTG GATAEDIALM RKTVGPNVGV 

       190        200        210        220 
KASGGVRTRE DADKMVAAGA SRVGASASVA IVLNDAKGAT DNY

« Hide

References

[1]"Genome sequence of Bacillus cereus B4264."
Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A., Ravel J., Sutton G.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B4264.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001176 Genomic DNA. Translation: ACK60866.1.
RefSeqYP_002366612.1. NC_011725.1.

3D structure databases

ProteinModelPortalB7HIT0.
ModBaseSearch...

Protein-protein interaction databases

STRINGB7HIT0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000107218; EBBACP00000107664; EBBACG00000107211.
GeneID7096962.
GenomeReviewsGene locus BCB4264_A1895 in contig CP001176_GR.
KEGGbcb:BCB4264_A1895.
PATRIC18875721. VBIBacCer117876_1769.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000000908.
HOGENOMHBG636421.
OMACLEAREN.
ProtClustDBPRK00507.

Family and domain databases

HAMAPMF_00114. DeoC_type1.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/AroFGH_arch.
IPR022979. Deoxyribose_phosphate_aldo_1.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01619.
PANTHERPTHR10889. DeoC. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. DeoC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDEOC_BACC4
AccessionPrimary (citable) accession number: B7HIT0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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