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B7HHG7

- HIS2_BACC4

UniProt

B7HHG7 - HIS2_BACC4

Protein

Phosphoribosyl-ATP pyrophosphatase

Gene

hisE

Organism
Bacillus cereus (strain B4264)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Catalytic activityi

    1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-AMP + diphosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoribosyl-ATP diphosphatase activity Source: UniProtKB-EC

    GO - Biological processi

    1. histidine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Amino-acid biosynthesis, Histidine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBCER405532:GI1K-1456-MONOMER.
    UniPathwayiUPA00031; UER00007.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoribosyl-ATP pyrophosphataseUniRule annotation (EC:3.6.1.31UniRule annotation)
    Short name:
    PRA-PHUniRule annotation
    Gene namesi
    Name:hisEUniRule annotation
    Ordered Locus Names:BCB4264_A1465
    OrganismiBacillus cereus (strain B4264)
    Taxonomic identifieri405532 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000007096: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 107107Phosphoribosyl-ATP pyrophosphatasePRO_1000135299Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi405532.BCB4264_A1465.

    Structurei

    3D structure databases

    ProteinModelPortaliB7HHG7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PRA-PH family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0140.
    HOGENOMiHOG000220965.
    KOiK01523.
    OMAiCKLLNHR.
    OrthoDBiEOG6CGCMH.

    Family and domain databases

    HAMAPiMF_01020. HisE.
    InterProiIPR008179. PRib-ATP_PPHydrolase.
    IPR021130. PRib-ATP_PPHydrolase-like.
    [Graphical view]
    PfamiPF01503. PRA-PH. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR03188. histidine_hisI. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B7HHG7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MENAFKLLYK TIEERKESPL PESYTNYLFS KGEDKILKKI GEECAEVIIA    50
    CKNNDKEEVV KEMVDVFYHC FVLLAEKNIA LEDVMREVKE RNGKLSRVGD 100
    RREIDTL 107
    Length:107
    Mass (Da):12,518
    Last modified:February 10, 2009 - v1
    Checksum:i97D18BBF614C5114
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001176 Genomic DNA. Translation: ACK61594.1.
    RefSeqiYP_002366194.1. NC_011725.1.

    Genome annotation databases

    EnsemblBacteriaiACK61594; ACK61594; BCB4264_A1465.
    GeneIDi7099028.
    KEGGibcb:BCB4264_A1465.
    PATRICi18874885. VBIBacCer117876_1351.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001176 Genomic DNA. Translation: ACK61594.1 .
    RefSeqi YP_002366194.1. NC_011725.1.

    3D structure databases

    ProteinModelPortali B7HHG7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 405532.BCB4264_A1465.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACK61594 ; ACK61594 ; BCB4264_A1465 .
    GeneIDi 7099028.
    KEGGi bcb:BCB4264_A1465.
    PATRICi 18874885. VBIBacCer117876_1351.

    Phylogenomic databases

    eggNOGi COG0140.
    HOGENOMi HOG000220965.
    KOi K01523.
    OMAi CKLLNHR.
    OrthoDBi EOG6CGCMH.

    Enzyme and pathway databases

    UniPathwayi UPA00031 ; UER00007 .
    BioCyci BCER405532:GI1K-1456-MONOMER.

    Family and domain databases

    HAMAPi MF_01020. HisE.
    InterProi IPR008179. PRib-ATP_PPHydrolase.
    IPR021130. PRib-ATP_PPHydrolase-like.
    [Graphical view ]
    Pfami PF01503. PRA-PH. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR03188. histidine_hisI. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Bacillus cereus B4264."
      Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A., Ravel J., Sutton G.
      Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: B4264.

    Entry informationi

    Entry nameiHIS2_BACC4
    AccessioniPrimary (citable) accession number: B7HHG7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: February 10, 2009
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3