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Protein

UvrABC system protein C

Gene

uvrC

Organism
Bacillus cereus (strain B4264)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein C
Short name:
Protein UvrC
Alternative name(s):
Excinuclease ABC subunit C
Gene namesi
Name:uvrC
Ordered Locus Names:BCB4264_A4628
OrganismiBacillus cereus (strain B4264)
Taxonomic identifieri405532 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000007096 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002005701 – 594UvrABC system protein CAdd BLAST594

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.

Structurei

3D structure databases

SMRiB7HF33.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 91GIY-YIGAdd BLAST78
Domaini196 – 231UVRAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.

Phylogenomic databases

HOGENOMiHOG000279960.
KOiK03703.
OMAiLFPIRQC.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

B7HF33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHEHLKEKLA ILPDQPGCYL MKDKQGTVIY VGKAKVLKNR VRSYFTGSHD
60 70 80 90 100
GKTLRLVGEI VDFEYIVTSS NLEALILELN LIKKYDPKYN IQLKDDKTYP
110 120 130 140 150
FIKITAEKQP RLLITRNVKK DKGKYFGPYP NAQSAHETKK LLDRMYPLRK
160 170 180 190 200
CTNMPDKVCL YYHMGQCLAP CVKEVTEEQN KEIVDEIIKF LNGGHKEVRS
210 220 230 240 250
ELEIKMYEAS EKLEFERAKE LRDQIAHIDA IMEKQKMIMS DLVDRDVFGY
260 270 280 290 300
AVDKGWMCVQ VFFVRKGKLI ERDVSMFPIY DEPEEGFLTF IGQFYENSSH
310 320 330 340 350
FKPKEIVVPG SIDSELVERF LEVEATQPKR GKKKDLVELA NKNAKIALEE
360 370 380 390 400
KFYLIERDEE RTIKAVDHLG KQLGIETPYR IEAFDNSNIQ GTNPVSAMIA
410 420 430 440 450
FIDGKPAKKE YRKYKIKTVQ GPDDYESMRE VVRRRYTRAL KENSPLPDLI
460 470 480 490 500
IIDGGKGHLA AASDILENEL GLYIPMAGLV KDDKHKTSHL IIGVPPEPVM
510 520 530 540 550
LERNSQEFYL LQRIQDEVHR FAITFHRQLH GKSVIQSALD DIPGIGDKRK
560 570 580 590
KVLLKHFGSL KKMKEASIEE FVEAGMPKNV AETIYTYLTD KKTL
Length:594
Mass (Da):68,474
Last modified:February 10, 2009 - v1
Checksum:i38EC3FC37883C295
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001176 Genomic DNA. Translation: ACK63190.1.
RefSeqiWP_000544298.1. NC_011725.1.

Genome annotation databases

EnsemblBacteriaiACK63190; ACK63190; BCB4264_A4628.
KEGGibcb:BCB4264_A4628.

Similar proteinsi

Entry informationi

Entry nameiUVRC_BACC4
AccessioniPrimary (citable) accession number: B7HF33
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: October 25, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families