Reviewed, UniProtKB/Swiss-Prot B7H3A6 (AROC_ACIB3)

Names and origin

Protein names

Recommended name:
    Chorismate synthase
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	ABBFA_001801

Organism

Acinetobacter baumannii (strain AB307-0294) [Complete proteome] [HAMAP]

Taxonomic identifier

557600 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity.
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 363	363	Chorismate synthase HAMAP MF_00300		PRO_1000119482

Sequences

	Sequence		Length	Mass (Da)
	B7H3A6-1 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 6EC0BA8A243EE418	FASTA	363	39,001
	10 20 30 40 50 60 MAGNSIGQLF RVTTCGESHG VGLMAIVDGV PPGLALTEED LQKDLDRRKP GTSKFATQRK 70 80 90 100 110 120 EPDQVEIISG VFEGKTTGTP IGLLIRNTDQ KSKDYGNIAQ TFRPGHADYT YTQKYGFRDY 130 140 150 160 170 180 RGGGRSSARE TAMRVAAGAI AKKYLAEKFG VLIRGHVTQI GNEVAEKLDW NEVPNNPFFC 190 200 210 220 230 240 GDVDAVPRFE ALVTSLREQG TSCGAKLEIL AEKVPVGWGE PVFDRLDADI AHAMMSINAV 250 260 270 280 290 300 KGVEIGDGFA VAGQFGHETR DELTSHGFLA NHAGGILGGI SSGQTIRVAI ALKPTASITT 310 320 330 340 350 360 PGKTINLNRE DTDVLTKGRH DPCVGVRATP IAEAMLAIVL MDHFLRHRAQ NADVVPPFAP IEP

References

[1]

"Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii." Adams M.D., Goglin K., Molyneaux N., Hujer K.M., Lavender H., Jamison J.J., MacDonald I.J., Martin K.M., Russo T., Campagnari A.A., Hujer A.M., Bonomo R.A., Gill S.R. J. Bacteriol. 190:8053-8064(2008) [PubMed: 18931120] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001172 Genomic DNA. Translation: ACJ56690.1.
RefSeq	YP_002325704.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	7060128.
GenomeReviews	Gene locus ABBFA_001801 in contig CP001172_GR.
KEGG	abb:ABBFA_001801.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_00300. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_ACIB3

Accession

Primary (citable) accession number: B7H3A6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	September 22, 2009
This is version 7 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)