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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Acinetobacter baumannii (strain AB307-0294)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Tricarboxylic acid cycle

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciABAU557600:GKC3-2690-MONOMER.
UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:ABBFA_002685
OrganismiAcinetobacter baumannii (strain AB307-0294)
Taxonomic identifieri557600 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacterAcinetobacter calcoaceticus/baumannii complex

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 546546Probable malate:quinone oxidoreductasePRO_1000191307Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiEOG6X6R8Z.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

B7GYG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKFLKYLLV LIILILIAGI VFLFRPIASK QVQTAKDEPV VDAVLVGGGI
60 70 80 90 100
MSATLGTYFT ELEPNWQIRM YERLDQVAQE SSNGFNNAGT GHSGFMEMNY
110 120 130 140 150
TEEKNGKMEI AKAEKVASQF EVAKQFWSYQ VKQGVLAEPK TFINPVPHIA
160 170 180 190 200
FVWGDNVKFL EKRYAAMIQS PLFKGMKFTE DPAVIKQWAP LVMTDRDPTQ
210 220 230 240 250
KVAATRMEVG SDVNYGSITK QLVNHLNQNP NFKLQTSTEV TGISQNDDKT
260 270 280 290 300
WTVSFKNLKT GKTDHVKTRF VFIGAGGAAV KLLQLTGLPE AKQYAGFPVG
310 320 330 340 350
GEFLITDNPA ITAQHTAKVY GRAELGAPPM SVPHIDTRYI DGKKYVLFGP
360 370 380 390 400
FATYSNKFLK NGSQLDLLAS TNKSNVLLMT TVGLENLDLV KYLVSQVMMS
410 420 430 440 450
DEDRLNELRK YYPDAKAEDW RLSQGGQRVQ IIKKEPGKPA TLQFGTEIFA
460 470 480 490 500
SKDGAVTALL GASPGASTSP YIMLNLLEKA FPQQTEGKWN QKLHEIVVSY
510 520 530 540
KQDLSKDPVL LDKVRQYTSS TLGLNYTSPF KAANDETAAA PVAKAN
Length:546
Mass (Da):60,467
Last modified:February 10, 2009 - v1
Checksum:iDCDB840DD8F98095
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001172 Genomic DNA. Translation: ACJ56713.1.
RefSeqiWP_000714075.1. NC_011595.1.

Genome annotation databases

EnsemblBacteriaiACJ56713; ACJ56713; ABBFA_002685.
KEGGiabb:ABBFA_002685.
PATRICi20706832. VBIAciBau42682_2596.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001172 Genomic DNA. Translation: ACJ56713.1.
RefSeqiWP_000714075.1. NC_011595.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACJ56713; ACJ56713; ABBFA_002685.
KEGGiabb:ABBFA_002685.
PATRICi20706832. VBIAciBau42682_2596.

Phylogenomic databases

HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiEOG6X6R8Z.

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.
BioCyciABAU557600:GKC3-2690-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AB307-0294.

Entry informationi

Entry nameiMQO_ACIB3
AccessioniPrimary (citable) accession number: B7GYG6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: November 11, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.