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B7GUB8 (B7GUB8_BIFLS) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length452 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site631Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site3031Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1651Substrate By similarity HAMAP-Rule MF_01201
Binding site3671Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue631N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
B7GUB8 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 633DFAC4F745E8D7

FASTA45248,122
        10         20         30         40         50         60 
MSMNAAPEIA FSSERGKANY EAARRQYPAQ AIVNLKTMRD NMAHLVSVVG GPTSGTAVMG 

        70         80         90        100        110        120 
VVKADAYGHG LLPTALAALA GGATWLGTAQ SHEALLLRRL GIGPDRCHIL TWVYNGAAAP 

       130        140        150        160        170        180 
FDDLIAADID VSVGSLSGIE ALAAAARRLG KPARVHVKVD SGFGRNGFTP AGFDAALAAL 

       190        200        210        220        230        240 
VPLAKEGVLR IVGQWSHLAV ADSPDVPEFV ASTDQQIATF KDFTRRMELA GIPPEIRHLA 

       250        260        270        280        290        300 
NTAATLDRPE IHFELTRPGI GLYGYEPDPA MGTPRDWHLT PAMRLQAQLG TVKDVEAGHG 

       310        320        330        340        350        360 
ISYGRTYLTP DNTSTAIVPL GYADGIHRSA SGFDMEGAKH VEKPGGPVRI MTAEGPRLYR 

       370        380        390        400        410        420 
VCGRVCMDQF IVDLHGSAAE LGVHEGDTVE LFGAGRGEDY VEPTADDWAR AADTISYEIF 

       430        440        450 
TCLRNRIPRL YEQAADALPA ADLAKLDPAT LL 

« Hide

References

[1]"The genome sequence of Bifidobacterium longum subsp. infantis reveals adaptations for milk utilization within the infant microbiome."
Sela D.A., Chapman J., Adeuya A., Kim J.H., Chen F., Whitehead T.R., Lapidus A., Rokhsar D.S., Lebrilla C.B., German J.B., Price N.P., Richardson P.M., Mills D.A.
Proc. Natl. Acad. Sci. U.S.A. 105:18964-18969(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12 [JGI].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001095 Genomic DNA. Translation: ACJ53064.1.
RefSeqYP_002323442.1. NC_011593.1.

3D structure databases

ProteinModelPortalB7GUB8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING391904.Blon_1997.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACJ53064; ACJ53064; Blon_1997.
GeneID7053651.
KEGGbln:Blon_1997.
PATRIC21125064. VBIBifLon71229_2010.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
KOK01775.
OMALWQLEAI.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycBLON391904:GCDR-2068-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB7GUB8_BIFLS
AccessionPrimary (citable) accession number: B7GUB8
Entry history
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: July 9, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)