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B7GPC4

- DCD_BIFLS

UniProt

B7GPC4 - DCD_BIFLS

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Protein

Deoxycytidine triphosphate deaminase

Gene

dcd

Organism
Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. dCTP deaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dUMP biosynthetic process Source: UniProtKB-UniPathway
  2. dUTP biosynthetic process Source: InterPro
  3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

BioCyciBLON391904:GCDR-2554-MONOMER.
UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxycytidine triphosphate deaminaseUniRule annotation (EC:3.5.4.13UniRule annotation)
Short name:
dCTP deaminaseUniRule annotation
Gene namesi
Name:dcdUniRule annotation
Ordered Locus Names:Blon_2465, BLIJ_2536
OrganismiBifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12)
Taxonomic identifieri391904 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
ProteomesiUP000001360: Chromosome, UP000007256: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 193193Deoxycytidine triphosphate deaminasePRO_1000123138Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi391904.Blon_2465.

Structurei

3D structure databases

ProteinModelPortaliB7GPC4.
SMRiB7GPC4. Positions 1-189.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0717.
HOGENOMiHOG000228601.
KOiK01494.
OMAiRPGMMIG.
OrthoDBiEOG67DPKR.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

B7GPC4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLLSDRDILA AQSAGHISLD PWTPEMVQPA SIDVRLDRYF RLFNNHAYTY
60 70 80 90 100
VDPAENQGAL TEQFEVAPDE PWILHPGEFA LGSTWEYVKL DPSIAARLEG
110 120 130 140 150
KSSLGRLGIL THSTAGFIDP GFEGHITLEL SNVSTLPVKL WPGMKIGQMC
160 170 180 190
FFQLSSPAEH PYGSKGTGSH YQGQRGPTPS RSYENFYRAH IDD
Length:193
Mass (Da):21,464
Last modified:February 10, 2009 - v1
Checksum:i48985FE84DBBFB63
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001095 Genomic DNA. Translation: ACJ53519.1.
AP010889 Genomic DNA. Translation: BAJ70113.1.
RefSeqiYP_002323897.1. NC_011593.1.
YP_005586283.1. NC_017219.1.

Genome annotation databases

EnsemblBacteriaiACJ53519; ACJ53519; Blon_2465.
BAJ70113; BAJ70113; BLIJ_2536.
GeneIDi12166872.
7054577.
KEGGibln:Blon_2465.
blon:BLIJ_2536.
PATRICi21126035. VBIBifLon71229_2476.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001095 Genomic DNA. Translation: ACJ53519.1 .
AP010889 Genomic DNA. Translation: BAJ70113.1 .
RefSeqi YP_002323897.1. NC_011593.1.
YP_005586283.1. NC_017219.1.

3D structure databases

ProteinModelPortali B7GPC4.
SMRi B7GPC4. Positions 1-189.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 391904.Blon_2465.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACJ53519 ; ACJ53519 ; Blon_2465 .
BAJ70113 ; BAJ70113 ; BLIJ_2536 .
GeneIDi 12166872.
7054577.
KEGGi bln:Blon_2465.
blon:BLIJ_2536.
PATRICi 21126035. VBIBifLon71229_2476.

Phylogenomic databases

eggNOGi COG0717.
HOGENOMi HOG000228601.
KOi K01494.
OMAi RPGMMIG.
OrthoDBi EOG67DPKR.

Enzyme and pathway databases

UniPathwayi UPA00610 ; UER00665 .
BioCyci BLON391904:GCDR-2554-MONOMER.

Family and domain databases

Gene3Di 2.70.40.10. 1 hit.
HAMAPi MF_00146. dCTP_deaminase.
InterProi IPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view ]
Pfami PF00692. dUTPase. 1 hit.
[Graphical view ]
SUPFAMi SSF51283. SSF51283. 1 hit.
TIGRFAMsi TIGR02274. dCTP_deam. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Bifidobacterium longum subsp. infantis reveals adaptations for milk utilization within the infant microbiome."
    Sela D.A., Chapman J., Adeuya A., Kim J.H., Chen F., Whitehead T.R., Lapidus A., Rokhsar D.S., Lebrilla C.B., German J.B., Price N.P., Richardson P.M., Mills D.A.
    Proc. Natl. Acad. Sci. U.S.A. 105:18964-18969(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12.

Entry informationi

Entry nameiDCD_BIFLS
AccessioniPrimary (citable) accession number: B7GPC4
Secondary accession number(s): E8MPN4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 10, 2009
Last modified: October 1, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3