ID   B7GNQ0_BIFLS            Unreviewed;       394 AA.
AC   B7GNQ0; E8MNY3;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   OrderedLocusNames=Blon_2348 {ECO:0000313|EMBL:ACJ53406.1};
OS   Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM
OS   1222 / NCTC 11817 / S12).
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=391904 {ECO:0000313|EMBL:ACJ53406.1, ECO:0000313|Proteomes:UP000001360};
RN   [1] {ECO:0000313|EMBL:ACJ53406.1, ECO:0000313|Proteomes:UP000001360}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12 [JGI]
RC   {ECO:0000313|Proteomes:UP000001360};
RX   PubMed=19033196; DOI=10.1073/pnas.0809584105;
RA   Sela D.A., Chapman J., Adeuya A., Kim J.H., Chen F., Whitehead T.R.,
RA   Lapidus A., Rokhsar D.S., Lebrilla C.B., German J.B., Price N.P.,
RA   Richardson P.M., Mills D.A.;
RT   "The genome sequence of Bifidobacterium longum subsp. infantis reveals
RT   adaptations for milk utilization within the infant microbiome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:18964-18969(2008).
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DR   EMBL; CP001095; ACJ53406.1; -; Genomic_DNA.
DR   AlphaFoldDB; B7GNQ0; -.
DR   SMR; B7GNQ0; -.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   KEGG; bln:Blon_2348; -.
DR   PATRIC; fig|391904.8.peg.2424; -.
DR   Proteomes; UP000001360; Chromosome.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000313|EMBL:ACJ53406.1};
KW   Hydrolase {ECO:0000313|EMBL:ACJ53406.1};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          67..345
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   394 AA;  41978 MW;  89467F072A925DE5 CRC64;
     MTENGMMNTN NTVCGANHDG AMSLAAPGDY GVACYRIPAL AEAPNGWILA AFDARPHNCQ
     DAPQANSIVQ RISKDGGRSF EPQHVVAAGH DGVDKYGYSD PSYVVDRQTG EVFLFFVKSY
     DAGFGTSQAG VDPSAREVLQ AAVTSSIDNG VTWSEPRIIT ADITNSESWI SRFASSGAGI
     QLTYGEHAGR LIQQYTIKEL DGRYRAVSVF SDDHGATWHA GTPVGDHMDE NKVVELSDGR
     VMLNSRSSDG NGCRYVAISR DGGATYGPVI RETQLPDPEN NAQIARAFPD APEGSAQAKV
     LLYSSSSPSD RIDGLVRVSI DDGKTWSAGR RFTTGPMAYS VIAALSHKAG GGYGLLYEGD
     NNNIMYTRIS LDWLNGQLNV DGIGGFPLSG EGGC
//