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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBLON391904:G1H61-2399-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Blon_2318, BLIJ_2393
OrganismiBifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12)
Taxonomic identifieri391904 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
Proteomesi
  • UP000001360 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001988751 – 620Arginine--tRNA ligaseAdd BLAST620

Proteomic databases

PRIDEiB7GNM0

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB7GNM0
SMRiB7GNM0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi147 – 157"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247214
KOiK01887

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B7GNM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPEALSELI SSIAHNLVAA GQAGTLTDDL IPPVDKLAVM RPKDRAHGDW
60 70 80 90 100
ASNIAMQLAK KAGMKPRDLA EPFAAALAEA DGIAKVEVAG PGFINITLDS
110 120 130 140 150
ASAAAVVDTV LAAGAVTDTD KHLNKVNEYG RNAHLGGQTL NLEFVSANPT
160 170 180 190 200
GPIHIGGTRW AAVGDAMARV LEANGAKVVR EYYFNDHGEQ INRFAKSLVA
210 220 230 240 250
AWAEANNLGD AGYQTETPCD GYKGAYINEI AARVQAEAES DGVDLTALAH
260 270 280 290 300
QDQGLNDDGE PLGEADTEVR EEFRKRAVPM MFDEIQKSMK DFRVNFDVWF
310 320 330 340 350
HENSLYADGK VDAAIEELKS RGDIFDKDGA TWFESTKHGD DKDRVIIKSN
360 370 380 390 400
GEFAYFAADI AYYWDKRHRA ENPADVAIYM LGADHHGYIG RMMAMCAAFG
410 420 430 440 450
DEPGKNMQIL IGQLVNVMKD GKPVRMSKRA GNVVTIDDLV SVVGVDAARY
460 470 480 490 500
SLARSDYNQN FDIDLALLAS HTNDNPVYYV QYAHARSKNV DRNAAVAGIS
510 520 530 540 550
YEGADLALLD TEADGEVLAA LAQFPSVLAT AADDRQPHKV ARYLEELAAT
560 570 580 590 600
YHKWYNVERV VPMVLTDPET RGDDEARKAL EIAKNPEPAR AAARLKLNDA
610 620
VQQVIANGLD LLGVTAPEKM
Length:620
Mass (Da):67,290
Last modified:February 10, 2009 - v1
Checksum:iC36B3ED666F3E332
GO

Sequence cautioni

The sequence BAJ69970 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001095 Genomic DNA Translation: ACJ53376.1
AP010889 Genomic DNA Translation: BAJ69970.1 Different initiation.
RefSeqiWP_012578546.1, NZ_JDTT01000025.1

Genome annotation databases

EnsemblBacteriaiACJ53376; ACJ53376; Blon_2318
BAJ69970; BAJ69970; BLIJ_2393
KEGGibln:Blon_2318
blon:BLIJ_2393
PATRICifig|391904.8.peg.2394

Similar proteinsi

Entry informationi

Entry nameiSYR_BIFLS
AccessioniPrimary (citable) accession number: B7GNM0
Secondary accession number(s): E8MNV4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 10, 2009
Last modified: May 23, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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