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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Anoxybacillus flavithermus (strain DSM 21510 / WK1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAFLA491915:G1GAW-2895-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Aflv_2742
OrganismiAnoxybacillus flavithermus (strain DSM 21510 / WK1)
Taxonomic identifieri491915 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeAnoxybacillus
Proteomesi
  • UP000000742 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001988711 – 556Arginine--tRNA ligaseAdd BLAST556

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi491915.Aflv_2742

Structurei

3D structure databases

ProteinModelPortaliB7GMJ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi132 – 142"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiHGMSTRQ
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B7GMJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIVEQMKQK LKEEIKEAVI RSGVATEADV PSVILETPKD KAHGDYSTNV
60 70 80 90 100
AMQLARVAKK APRMIAEDIV RHFNGEAVFV KKVDIAGPGF INFYMDNRYL
110 120 130 140 150
TELVPAILQA GDAYGETNVG QGQKVQVEFV SANPTGSLHL GHARGAAVGD
160 170 180 190 200
SLCNILKKAG FDVTREYYIN DAGNQIANLA KSVEARYFQA LGIKKDMPED
210 220 230 240 250
GYFGEDIIEL GKKLAEEHGD KFVALDEQER LQLFREYGLA FEMDKIKKDL
260 270 280 290 300
ADFRVTFDVW YSETSLYHNG KIDKALETLR EKGHIYEQDG ATWFRSTTFG
310 320 330 340 350
DDKDRVLIKQ DGTYTYLLPD IAYHQDKLER GFEKIINIWG ADHHGYIPRM
360 370 380 390 400
KAAIAALGYD PDVLEVEIIQ LVSLYQNGEK VRMSKRTGKA VTLRDLMEEV
410 420 430 440 450
GLDATRYFFA MRSSDTHLDF DMDLAVSQSN ENPVYYAQYA HARVCSMLRQ
460 470 480 490 500
GEEQGWRYDG DLSFTYELAE KEIDLLKKLG EFPSAVAEAA VKRSPHRMTN
510 520 530 540 550
YIFDLASALH SFYNAEKVLD AANVEKSRAR LALMKAVQIT LKNALALVGV

HAPEKM
Length:556
Mass (Da):62,636
Last modified:February 10, 2009 - v1
Checksum:i28CD7D5B34821F5E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000922 Genomic DNA Translation: ACJ35095.1
RefSeqiWP_012576219.1, NC_011567.1

Genome annotation databases

EnsemblBacteriaiACJ35095; ACJ35095; Aflv_2742
KEGGiafl:Aflv_2742
PATRICifig|491915.6.peg.2826

Similar proteinsi

Entry informationi

Entry nameiSYR_ANOFW
AccessioniPrimary (citable) accession number: B7GMJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: March 28, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health