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B7GMJ3 (SYR_ANOFW) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Aflv_2742
OrganismAnoxybacillus flavithermus (strain DSM 21510 / WK1) [Complete proteome] [HAMAP]
Taxonomic identifier491915 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeAnoxybacillus

Protein attributes

Sequence length556 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 556556Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000198871

Regions

Motif132 – 14211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B7GMJ3 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 28CD7D5B34821F5E

FASTA55662,636
        10         20         30         40         50         60 
MNIVEQMKQK LKEEIKEAVI RSGVATEADV PSVILETPKD KAHGDYSTNV AMQLARVAKK 

        70         80         90        100        110        120 
APRMIAEDIV RHFNGEAVFV KKVDIAGPGF INFYMDNRYL TELVPAILQA GDAYGETNVG 

       130        140        150        160        170        180 
QGQKVQVEFV SANPTGSLHL GHARGAAVGD SLCNILKKAG FDVTREYYIN DAGNQIANLA 

       190        200        210        220        230        240 
KSVEARYFQA LGIKKDMPED GYFGEDIIEL GKKLAEEHGD KFVALDEQER LQLFREYGLA 

       250        260        270        280        290        300 
FEMDKIKKDL ADFRVTFDVW YSETSLYHNG KIDKALETLR EKGHIYEQDG ATWFRSTTFG 

       310        320        330        340        350        360 
DDKDRVLIKQ DGTYTYLLPD IAYHQDKLER GFEKIINIWG ADHHGYIPRM KAAIAALGYD 

       370        380        390        400        410        420 
PDVLEVEIIQ LVSLYQNGEK VRMSKRTGKA VTLRDLMEEV GLDATRYFFA MRSSDTHLDF 

       430        440        450        460        470        480 
DMDLAVSQSN ENPVYYAQYA HARVCSMLRQ GEEQGWRYDG DLSFTYELAE KEIDLLKKLG 

       490        500        510        520        530        540 
EFPSAVAEAA VKRSPHRMTN YIFDLASALH SFYNAEKVLD AANVEKSRAR LALMKAVQIT 

       550 
LKNALALVGV HAPEKM 

« Hide

References

[1]"Encapsulated in silica: genome, proteome and physiology of the thermophilic bacterium Anoxybacillus flavithermus WK1."
Saw J.H., Mountain B.W., Feng L., Omelchenko M.V., Hou S., Saito J.A., Stott M.B., Li D., Zhao G., Wu J., Galperin M.Y., Koonin E.V., Makarova K.S., Wolf Y.I., Rigden D.J., Dunfield P.F., Wang L., Alam M.
Genome Biol. 9:R161.1-R161.16(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 21510 / WK1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000922 Genomic DNA. Translation: ACJ35095.1.
RefSeqYP_002317080.1. NC_011567.1.

3D structure databases

ProteinModelPortalB7GMJ3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING491915.Aflv_2742.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACJ35095; ACJ35095; Aflv_2742.
GeneID7039015.
KEGGafl:Aflv_2742.
PATRIC20957482. VBIAnoFla45531_2826.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycAFLA491915:GHEO-2831-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_ANOFW
AccessionPrimary (citable) accession number: B7GMJ3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: May 14, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries