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B7GKA2 (PSD_ANOFW) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:Aflv_0809
OrganismAnoxybacillus flavithermus (strain DSM 21510 / WK1) [Complete proteome] [HAMAP]
Taxonomic identifier491915 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Anoxybacillus

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 225225Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000131338
Chain226 – 26540Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000131339

Sites

Site225 – 2262Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2261Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
B7GKA2 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: A2441A5BE35DFE6B

FASTA26530,642
        10         20         30         40         50         60 
MVKWLYQLFI ELTNHAWTSK CLASFTRSKW SRLFISSYAK VYKINKEEME KKLHEYETLQ 

        70         80         90        100        110        120 
QLFVRTLKKG LRPIDTHPDS VVSPVDAVIE DVGIITDQKE IIVKGKTYSI REMLGDDQIA 

       130        140        150        160        170        180 
EKYLHGTFII LYLSPSHYHR IHSPICGEVV KQWELGGKSY PVNRLGLKYG KAPLSKNYRR 

       190        200        210        220        230        240 
ITELYTNGMY TAIVKVGAMF VNSIELTHEH DHVKKGEEIG YFSFGSTVVL LFEKDVFTLD 

       250        260 
EQIVPPFEVK MGQRIGFLAQ KKKSQ

« Hide

References

[1]"Encapsulated in silica: genome, proteome and physiology of the thermophilic bacterium Anoxybacillus flavithermus WK1."
Saw J.H., Mountain B.W., Feng L., Omelchenko M.V., Hou S., Saito J.A., Stott M.B., Li D., Zhao G., Wu J., Galperin M.Y., Koonin E.V., Makarova K.S., Wolf Y.I., Rigden D.J., Dunfield P.F., Wang L., Alam M.
Genome Biol. 9:R161.1-R161.16(2008) [PubMed: 19014707] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 21510 / WK1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000922 Genomic DNA. Translation: ACJ33187.1.
RefSeqYP_002315172.1. NC_011567.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB7GKA2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7037066.
GenomeReviewsGene locus Aflv_0809 in contig CP000922_GR.
KEGGafl:Aflv_0809.
PATRIC20953437. VBIAnoFla45531_0829.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG302256.
ProtClustDBPRK03140.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_ANOFW
AccessionPrimary (citable) accession number: B7GKA2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: January 25, 2012
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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