B7GK04 (GLGA_ANOFW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	Aflv_0376

Organism

Anoxybacillus flavithermus (strain DSM 21510 / WK1) [Complete proteome] [HAMAP]

Taxonomic identifier

491915 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Anoxybacillus

Protein attributes

Sequence length	484 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	starch synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 484	484	Glycogen synthase HAMAP MF_00484		PRO_1000126054
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	B7GK04 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: A4080D4DB8086394	FASTA	484	56,136
	10 20 30 40 50 60 MKVLFVVSEC VPFVKTGGLA DVAGALPKEL KKLGTDVRVM LPKYGLIPQH MRQKMKKIAE 70 80 90 100 110 120 LVVRVGWRRQ YCGIEQLEHE GITYYFVDNE YYFKRDSLYG HYDDGERFSY FCRAVLDCLP 130 140 150 160 170 180 VIDFQPNVIH CHDWHTGMIP FLLREEYMRN SFYAQMKTVF TIHNLQFQGI FPREILGDLL 190 200 210 220 230 240 NLSDRYFSIE HLEFYGHVSF MKGALVSAHL ITTVSPTYKE EIQTPYYGER LDGLLRARSS 250 260 270 280 290 300 HLVGILNGID DEIYNPKKDP YIAVPYDVTT IARKSINKRA LQQHFSLPSE EDVPVIAIVS 310 320 330 340 350 360 RLTKQKGLDL VKCVFHEIIA EHVQMIILGT GEWEFEQFFQ DMTMTYPDRV RVYIGFSEQL 370 380 390 400 410 420 AHQIYAGADM FLMPSKFEPC GLGQMIAMRY GAVPIVRETG GLNDTVQSFN ELTKEGTGFT 430 440 450 460 470 480 FKNFNAHDML YTIQRARSFY EQKEIWETIM KQAMSRDYSW AKSAFKYNQL YDELMAGSGI YVHE

References

[1]

"Encapsulated in silica: genome, proteome and physiology of the thermophilic bacterium Anoxybacillus flavithermus WK1." Saw J.H., Mountain B.W., Feng L., Omelchenko M.V., Hou S., Saito J.A., Stott M.B., Li D., Zhao G., Wu J., Galperin M.Y., Koonin E.V., Makarova K.S., Wolf Y.I., Rigden D.J., Dunfield P.F., Wang L., Alam M. Genome Biol. 9:R161.1-R161.16(2008) [PubMed: 19014707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 21510 / WK1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000922 Genomic DNA. Translation: ACJ32760.1.
RefSeq	YP_002314745.1. NC_011567.1.
3D structure databases
ProteinModelPortal	B7GK04.
ModBase	Search...
Protein-protein interaction databases
STRING	B7GK04.
Protein family/group databases
CAZy	GT5. Glycosyltransferase Family 5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7036633.
GenomeReviews	Gene locus Aflv_0376 in contig CP000922_GR.
KEGG	afl:Aflv_0376.
PATRIC	20952549. VBIAnoFla45531_0386.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG596384.
ProtClustDB	PRK00654.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth. [Tree]
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
KO	K00703.
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. GlgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_ANOFW

Accession

Primary (citable) accession number: B7GK04

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program