Reviewed, UniProtKB/Swiss-Prot B7GHN1 (KCY_ANOFW)

Names and origin

Protein names

Recommended name:
    Cytidylate kinase
      Short name=CK
    EC=2.7.4.14
Alternative name(s):
    Cytidine monophosphate kinase
      Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	Aflv_1077

Organism

Anoxybacillus flavithermus (strain DSM 21510 / WK1) [Complete proteome] [HAMAP]

Taxonomic identifier

491915 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Anoxybacillus

Protein attributes

Sequence length	225 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrimidine nucleotide metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP cytidylate kinase activity Inferred from electronic annotation. Source: HAMAP shikimate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 225	225	Cytidylate kinase HAMAP MF_00238		PRO_1000119006
Regions
	Nucleotide binding	11 – 19	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	B7GHN1-1 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 88C9F49A42FB7502	FASTA	225	25,088
	10 20 30 40 50 60 MEKKISIAID GPAAAGKSTV AKRLAEALSY VYIDTGAMYR ALTYCALQRG VDVHNEKQLM 70 80 90 100 110 120 NVLHDTYIEL KPSPSGQLVF ANGENVTEAI RTNDVTNNVS YVAKHPAVRE EMVKRQRELG 130 140 150 160 170 180 QHGGVVMDGR DIGTHVLPHA EVKIFLLASV EERAKRRHEE NVLRGIPSDF EQLKEEIARR 190 200 210 220 DQIDSERAVA PLKKAEDAIE IDTTSLSIDE VVDRIMCIVQ ERVEG

References

[1]

"Encapsulated in silica: genome, proteome and physiology of the thermophilic bacterium Anoxybacillus flavithermus WK1." Saw J.H., Mountain B.W., Feng L., Omelchenko M.V., Hou S., Saito J.A., Stott M.B., Li D., Zhao G., Wu J., Galperin M.Y., Koonin E.V., Makarova K.S., Wolf Y.I., Rigden D.J., Dunfield P.F., Wang L., Alam M. Genome Biol. 9:RESEARCH161.1-RESEARCH161.16(2008) [PubMed: 19014707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000922 Genomic DNA. Translation: ACJ33453.1.
RefSeq	YP_002315438.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	7037334.
GenomeReviews	Gene locus Aflv_1077 in contig CP000922_GR.
KEGG	afl:Aflv_1077.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_00238. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kin_d. IPR000623. Shik_kinase. [Graphical view]
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. PF01202. SKI. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_ANOFW

Accession

Primary (citable) accession number: B7GHN1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	June 16, 2009
This is version 6 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)