Reviewed, UniProtKB/Swiss-Prot B7GGR2 (ACKA_ANOFW)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	Aflv_0480

Organism

Anoxybacillus flavithermus (strain DSM 21510 / WK1) [Complete proteome] [HAMAP]

Taxonomic identifier

491915 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Anoxybacillus

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Acetate kinase HAMAP MF_00020		PRO_1000116385

Sequences

	Sequence		Length	Mass (Da)
	B7GGR2-1 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: D7DA3F03BEB565F8	FASTA	397	43,349
	10 20 30 40 50 60 MPKVIAINAG SSSLKFQLFN MPSEEVLTKG VVERIGFEDA IFNITVNGEK IKEVTPIPDH 70 80 90 100 110 120 AVAVKMLLDK LIELGIIQSF DEIEGIGHRV VHGGEKFSDS VLITDETLKE IEDLSDLAPL 130 140 150 160 170 180 HNPANVVGIK AFREVLPNVP AVAVFDTAFH QTMPEQSFLY SLPYEYYEKF GIRKYGFHGT 190 200 210 220 230 240 SHKYVTQRAA ELLGRPIEQL RLISCHLGNG ASIAAVEGGK SIDTSMGFTP LAGVAMGTRS 250 260 270 280 290 300 GNIDPALIPY IMQKTGKTAE EVIDILNKKS GMLGLTGFSS DLRDIEEAAA KGDQRAELAL 310 320 330 340 350 360 EVFAGRIHKY IGSYAARMCG VDAIIFTAGI GENSDIVRAK VLRGLEFMGV YWDPALNKVR 370 380 390 GKEAFISYPH SPVKVLVIPT NEEVMIARDV MRLANLA

References

[1]

"Encapsulated in silica: genome, proteome and physiology of the thermophilic bacterium Anoxybacillus flavithermus WK1." Saw J.H., Mountain B.W., Feng L., Omelchenko M.V., Hou S., Saito J.A., Stott M.B., Li D., Zhao G., Wu J., Galperin M.Y., Koonin E.V., Makarova K.S., Wolf Y.I., Rigden D.J., Dunfield P.F., Wang L., Alam M. Genome Biol. 9:RESEARCH161.1-RESEARCH161.16(2008) [PubMed: 19014707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000922 Genomic DNA. Translation: ACJ32864.1.
RefSeq	YP_002314849.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	7036737.
GenomeReviews	Gene locus Aflv_0480 in contig CP000922_GR.
KEGG	afl:Aflv_0480.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_ANOFW

Accession

Primary (citable) accession number: B7GGR2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	October 13, 2009
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)