ID   B7FXS5_PHATC            Unreviewed;      1307 AA.
AC   B7FXS5;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   RecName: Full=ATP-dependent DNA ligase family profile domain-containing protein {ECO:0000259|PROSITE:PS50160};
GN   ORFNames=PHATRDRAFT_45463 {ECO:0000313|EMBL:EEC48802.1},
GN   PHATRDRAFT_50218 {ECO:0000313|EMBL:EEC43238.1};
OS   Phaeodactylum tricornutum (strain CCAP 1055/1).
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC   Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae;
OC   Phaeodactylum.
OX   NCBI_TaxID=556484 {ECO:0000313|EMBL:EEC48802.1, ECO:0000313|Proteomes:UP000000759};
RN   [1] {ECO:0000313|EMBL:EEC48802.1, ECO:0000313|Proteomes:UP000000759}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCAP 1055/1 {ECO:0000313|EMBL:EEC48802.1,
RC   ECO:0000313|Proteomes:UP000000759};
RX   PubMed=18923393; DOI=10.1038/nature07410;
RA   Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA   Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA   Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA   Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA   Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA   Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA   Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA   La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA   Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA   Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA   Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA   Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA   Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA   Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA   Grigoriev I.V.;
RT   "The Phaeodactylum genome reveals the evolutionary history of diatom
RT   genomes.";
RL   Nature 456:239-244(2008).
RN   [2] {ECO:0000313|Proteomes:UP000000759}
RP   GENOME REANNOTATION.
RC   STRAIN=CCAP 1055/1 {ECO:0000313|Proteomes:UP000000759};
RG   Diatom Consortium;
RA   Grigoriev I., Grimwood J., Kuo A., Otillar R.P., Salamov A., Detter J.C.,
RA   Lindquist E., Shapiro H., Lucas S., Glavina del Rio T., Pitluck S.,
RA   Rokhsar D., Bowler C.;
RL   Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC       {ECO:0000256|ARBA:ARBA00004229}.
CC   -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC       {ECO:0000256|ARBA:ARBA00007572}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM000630; EEC43238.1; -; Genomic_DNA.
DR   EMBL; CM000610; EEC48802.1; -; Genomic_DNA.
DR   RefSeq; XP_002179816.1; XM_002179780.1.
DR   RefSeq; XP_002185106.1; XM_002185070.1.
DR   STRING; 556484.B7FXS5; -.
DR   PaxDb; 2850-Phatr45463; -.
DR   EnsemblProtists; Phatr3_J45463.t1; Phatr3_J45463.p1; Phatr3_J45463.
DR   EnsemblProtists; Phatr3_J50218.t1; Phatr3_J50218.p1; Phatr3_J50218.
DR   GeneID; 7199084; -.
DR   GeneID; 7200566; -.
DR   KEGG; pti:PHATRDRAFT_45463; -.
DR   KEGG; pti:PHATRDRAFT_50218; -.
DR   eggNOG; KOG0966; Eukaryota.
DR   HOGENOM; CLU_261042_0_0_1; -.
DR   InParanoid; B7FXS5; -.
DR   OMA; PMASERT; -.
DR   OrthoDB; 8251at2759; -.
DR   Proteomes; UP000000759; Chromosome 28.
DR   Proteomes; UP000000759; Chromosome 7.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:InterPro.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR029710; LIG4.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   PANTHER; PTHR45997; DNA LIGASE 4; 1.
DR   PANTHER; PTHR45997:SF1; DNA LIGASE 4; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000759}.
FT   DOMAIN          691..758
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50160"
FT   REGION          1..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..28
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..45
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1307 AA;  148327 MW;  A768758D16E74214 CRC64;
     MPNSIHLASR EDARGDQDER HYFDGPLLDI EDDEYDVEDE PLAEVDNPTT DAGPKPSYME
     PSYERASAVS FSRLSQQMEY LYRLKTQNVV HPPDKVSKLK RLLPPALISK ISRPTKTSDP
     PQSLFPILRL LLPERDGSRR IFTKENTLAK AYGRAFGLPP ASTDYQKLLY YSDPHIVGSK
     STGTGDFSEV LRQVLEKRIS LQKNGSGVTV GQVNALLDEL AVIGKPPTRS NHDWRNREAE
     LNDFQLKPKN SASKAELQAN WVTKLHCLGL TPLEHKWIIR IILERLQITL GSTVILAWYH
     PLAPSFWSAH NSLKAVCNKL CQPGVFELRH NLAEDGGDDD EAPSTLAPYF KSTHLTHVQL
     GNPFSPMASE RTGFHTVLSD MSSRHRDFTG EERCYRYEAV IRSLAFKFPT FAIETKLDGE
     RLLVHYFRNG TVKLHTRQGN WYSELYSPVL GPALRRAVGK HDLDLILDGE VLAWDNERHE
     TVPFGNNRTI AKMRYSWMRK AGILDERDIN LHNGENDVKR INSSNSWNTH NTRCDEVGEE
     CWLQFIAFDV LYINGPHALD FLSKTVSSFA LAKKQSGSIV DLECLERKKI LYELIDEQDN
     EVEIVPTVVV RPNGQTSPGH DYFRLSNPTM ECGFPARDLD SIARMFHQPK NDLGTIDAQR
     RHGLSDELMR KARAQAVESH YRKVVEDMRL EGLLFKDLST PYILDKISRS FGYWRKFKPD
     YFNGSVASDL DVVIIGAYFA SGLRLSGKPS SFLCACTDSC DSEYYFPMCK VNAGSMDRNS
     FSQLLYETGF RAPCDRPDPN AEESKMEYGR WFREEDHGKA LPDFITDRSH QNNSRDGRWR
     FRKEDYPDIW INPSDSCVLT LNAGDIVSSE AFPSGLTLRF PRIVKVRIGA DTKDPTEVES
     DRSLQKILQQ VLKERCESKG EANGICSTKS FTRAKAQQFC RFLTEEEYVQ GKNRKNSTGR
     SKTLLLVPTS QQVMLSESKV LTGLSFHVLD GRYSIDSDDV AVDEATEEGW LEKALSVRSS
     NDVKHFIARH NGKVLLNPDS SMFVIGGSET DARVITYIQA INRARTSLDR RTKETDRYRR
     IAGSAGVLRW TFVFSFVQSH LGDADVSTSA LMFNPTMLDF LKRAQIEAEE LEFMADLSSK
     SSLRRALGLT SKRKRTGSDS FFLGDWRERV FSCLPTMERC ILSCRVQSVG PFKSVKADTP
     SNVIPSVVCP VTVNDDTIES VLPLARMMGA VVVREPRKDL THVVCHMIVH DIVKHKRGMS
     LDLFENREQG TAFKRILDDL QIKHNLSHDI LFVTPNWIRA QWPSHAR
//