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B6YX13 (B6YX13_THEON) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
EC=2.5.1.19 HAMAP MF_00210
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP MF_00210
Gene names
Name:aroA HAMAP MF_00210
Ordered Locus Names:TON_1138
OrganismThermococcus onnurineus (strain NA1) [Complete proteome] [HAMAP]
Taxonomic identifier523850 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210 RuleBase RU004116

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family. HAMAP MF_00210 RuleBase RU004164

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis HAMAP MF_00210
   Cellular componentCytoplasm HAMAP MF_00210
   Molecular functionTransferase HAMAP MF_00210
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B6YX13 [UniParc].

Last modified January 20, 2009. Version 1.
Checksum: FBA6E1198A1BDCBF

FASTA40243,719
        10         20         30         40         50         60 
MGVIIRPVGE VTGEVEAPPS KSYTHRAYFL ALLAEGRSKV KRPLVSDDTL ATLNAIRAFG 

        70         80         90        100        110        120 
ASVEGESIIP PEWPKGAFID AHESGTTARI ALAVASIGGG ESTVNGGRRL RERPFGELVR 

       130        140        150        160        170        180 
ALRKAGAEIE GERLPLRVIG RNLRRRDVEV DASTSSQFAT ALLIIGAKVG MEVLIKRSVS 

       190        200        210        220        230        240 
RPYIEVTART LKAFGADFRR EGFDFYIEPG ITGTSFTVPG DYSSASFFLA AGALYGRVKI 

       250        260        270        280        290        300 
RNLDPKDVQA DRAIIDALRE FGAEVRVGRN YVEAEKGELR GVEMDCSDFP DLFPVLAVVA 

       310        320        330        340        350        360 
SYAEGRSVLR ARQLRFKESD RVRAMAVNLS RMGIRVRELP DGLEIEGGRP KGGQFETFND 

       370        380        390        400 
HRIAMAMVVA ALGARGESVI PETGSVSKSY PGFFNDLRRL VG

« Hide

References

[1]"The complete genome sequence of Thermococcus onnurineus NA1 reveals a mixed heterotrophic and carboxydotrophic metabolism."
Lee H.S., Kang S.G., Bae S.S., Lim J.K., Cho Y., Kim Y.J., Jeon J.H., Cha S.-S., Kwon K.K., Kim H.-T., Park C.-J., Lee H.-W., Kim S.I., Chun J., Colwell R.R., Kim S.-J., Lee J.-H.
J. Bacteriol. 190:7491-7499(2008) [PubMed: 18790866] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000855 Genomic DNA. Translation: ACJ16626.1.
RefSeqYP_002307523.1. NC_011529.1.

3D structure databases

ProteinModelPortalB6YX13.
ModBaseSearch...

Protein-protein interaction databases

STRINGB6YX13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7018160.
GenomeReviewsGene locus TON_1138 in contig CP000855_GR.
KEGGton:TON_1138.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMAERKSWSF.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB6YX13_THEON
AccessionPrimary (citable) accession number: B6YX13
Entry history
Integrated into UniProtKB/TrEMBL: January 20, 2009
Last sequence update: January 20, 2009
Last modified: November 16, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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