B6YUP1 (B6YUP1_THEON) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE HAMAP MF_00060
EC=3.1.3.5 HAMAP MF_00060

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase HAMAP MF_00060

Gene names

Name:	surE HAMAP MF_00060
Ordered Locus Names:	TON_0590

Organism

Thermococcus onnurineus (strain NA1) [Complete proteome] [HAMAP]

Taxonomic identifier

523850 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	260 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity. HAMAP MF_00060
Subcellular location	Cytoplasm By similarity HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family. HAMAP MF_00060

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00060
Ligand	Metal-binding HAMAP MF_00060 Nucleotide-binding HAMAP MF_00060
Molecular function	Hydrolase HAMAP MF_00060
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	9	1	Divalent metal cation By similarity HAMAP MF_00060
	Metal binding	10	1	Divalent metal cation By similarity HAMAP MF_00060
	Metal binding	40	1	Divalent metal cation By similarity HAMAP MF_00060
	Metal binding	94	1	Divalent metal cation By similarity HAMAP MF_00060

Sequences

	Sequence		Length	Mass (Da)
	B6YUP1 [UniParc]. Last modified January 20, 2009. Version 1. Checksum: 5D9D11E744648C7E	FASTA	260	28,579
	10 20 30 40 50 60 MPRILITNDD GIYSKGIRAA VEAVKDLGEV YVVAPLFQRS ASGRAMTLHK PLRAKLVNVP 70 80 90 100 110 120 GAKVAYGLDG MPVDCVIFAL ARFTHFDLAI SGINLGENLS TEITVSGTAS AAIETATHGI 130 140 150 160 170 180 PSIAISLEVD WRKTLSEGEG IDFSVASHFL RRITRTVLEK GLPKGVDMLN VNIPNDATPE 190 200 210 220 230 240 TGIKVTRLAR RRYRPTIEER IDPRGYPYYW IVGRKCEKFE PGTDAYTLKV ERKVSVTPIN 250 260 IDMTAGVDLK EVERLLRSGL

References

[1]

"The complete genome sequence of Thermococcus onnurineus NA1 reveals a mixed heterotrophic and carboxydotrophic metabolism." Lee H.S., Kang S.G., Bae S.S., Lim J.K., Cho Y., Kim Y.J., Jeon J.H., Cha S.-S., Kwon K.K., Kim H.-T., Park C.-J., Lee H.-W., Kim S.I., Chun J., Colwell R.R., Kim S.-J., Lee J.-H. J. Bacteriol. 190:7491-7499(2008) [PubMed: 18790866] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000855 Genomic DNA. Translation: ACJ16077.1.
RefSeq	YP_002306974.1. NC_011529.1.
3D structure databases
ProteinModelPortal	B6YUP1.
ModBase	Search...
Protein-protein interaction databases
STRING	B6YUP1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7016888.
GenomeReviews	Gene locus TON_0590 in contig CP000855_GR.
KEGG	ton:TON_0590.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG600532.
OMA	PINIDMT.
ProtClustDB	PRK00346.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B6YUP1_THEON

Accession

Primary (citable) accession number: B6YUP1

Entry history

Integrated into UniProtKB/TrEMBL:	January 20, 2009
Last sequence update:	January 20, 2009
Last modified:	November 16, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)