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B6YT45

- GPI_THEON

UniProt

B6YT45 - GPI_THEON

Protein

Glucose-6-phosphate isomerase

Gene

pgiA

Organism
Thermococcus onnurineus (strain NA1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (20 Jan 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi88 – 881IronUniRule annotation
    Metal bindingi90 – 901IronUniRule annotation
    Metal bindingi97 – 971IronUniRule annotation
    Metal bindingi136 – 1361IronUniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP
    2. iron ion binding Source: InterPro

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Keywords - Ligandi

    Iron, Metal-binding

    Enzyme and pathway databases

    BioCyciTONN523850:GC7X-264-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiAUniRule annotation
    Ordered Locus Names:TON_0247
    OrganismiThermococcus onnurineus (strain NA1)
    Taxonomic identifieri523850 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
    ProteomesiUP000002727: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 189189Glucose-6-phosphate isomerasePRO_1000145512Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi523850.TON_0247.

    Structurei

    3D structure databases

    ProteinModelPortaliB6YT45.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the archaeal-type GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2140.
    HOGENOMiHOG000243903.
    KOiK06859.
    OMAiYPADAGH.

    Family and domain databases

    Gene3Di2.60.120.10. 1 hit.
    HAMAPiMF_01410. G6P_isomerase_arch.
    InterProiIPR010551. G6P_isomerase_prok.
    IPR016758. G6P_isomerase_subgr.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view]
    PfamiPF06560. GPI. 1 hit.
    [Graphical view]
    PIRSFiPIRSF019325. Glucose-6-phosphate_isomerase. 1 hit.
    SUPFAMiSSF51182. SSF51182. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B6YT45-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEYKAPIGVK IDLETGVIPG AKKLVRRLSD LKGYFIDEEA YNELLREDPV    50
    VYEVYAIEQE EKDGDLNFAT TVLYPGKVGK EFFFTKGHYH AKADRAEIYY 100
    AIKGKGGMLL QTPEGNAKWV PMEPGTVVYV PPYWAHRTVN TGDEPFIFLA 150
    IYPADAGHDY GSIKEKGFSK LVIEEGGEVK VVDNPKWKA 189
    Length:189
    Mass (Da):21,253
    Last modified:January 20, 2009 - v1
    Checksum:iB4AE78E487571D65
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000855 Genomic DNA. Translation: ACJ15732.1.
    RefSeqiYP_002306629.1. NC_011529.1.

    Genome annotation databases

    EnsemblBacteriaiACJ15732; ACJ15732; TON_0247.
    GeneIDi7017909.
    KEGGiton:TON_0247.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000855 Genomic DNA. Translation: ACJ15732.1 .
    RefSeqi YP_002306629.1. NC_011529.1.

    3D structure databases

    ProteinModelPortali B6YT45.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 523850.TON_0247.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACJ15732 ; ACJ15732 ; TON_0247 .
    GeneIDi 7017909.
    KEGGi ton:TON_0247.

    Phylogenomic databases

    eggNOGi COG2140.
    HOGENOMi HOG000243903.
    KOi K06859.
    OMAi YPADAGH.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci TONN523850:GC7X-264-MONOMER.

    Family and domain databases

    Gene3Di 2.60.120.10. 1 hit.
    HAMAPi MF_01410. G6P_isomerase_arch.
    InterProi IPR010551. G6P_isomerase_prok.
    IPR016758. G6P_isomerase_subgr.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view ]
    Pfami PF06560. GPI. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF019325. Glucose-6-phosphate_isomerase. 1 hit.
    SUPFAMi SSF51182. SSF51182. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of Thermococcus onnurineus NA1 reveals a mixed heterotrophic and carboxydotrophic metabolism."
      Lee H.S., Kang S.G., Bae S.S., Lim J.K., Cho Y., Kim Y.J., Jeon J.H., Cha S.-S., Kwon K.K., Kim H.-T., Park C.-J., Lee H.-W., Kim S.I., Chun J., Colwell R.R., Kim S.-J., Lee J.-H.
      J. Bacteriol. 190:7491-7499(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NA1.

    Entry informationi

    Entry nameiGPI_THEON
    AccessioniPrimary (citable) accession number: B6YT45
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: January 20, 2009
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3