Reviewed, UniProtKB/Swiss-Prot B6YSM2 (RNP1_THEON)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 1
      Short name=RNase P component 1
    EC=3.1.26.5

Gene names

Name:	rnp1
Ordered Locus Names:	TON_1969

Organism

Thermococcus onnurineus (strain NA1) [Complete proteome] [HAMAP]

Taxonomic identifier

523850 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	125 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00754
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Cellular component	ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro ribonuclease P complex Inferred from electronic annotation. Source: InterPro
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 125	125	Ribonuclease P protein component 1 HAMAP MF_00754		PRO_1000194586

Sequences

	Sequence		Length	Mass (Da)
	B6YSM2-1 [UniParc]. Last modified January 20, 2009. Version 1. Checksum: E67381243AA30B32	FASTA	125	14,687
	10 20 30 40 50 60 MRRNGKEGKD RAPGRPQRKG QEVASRPWIF RGLDRNRVTA KNILWHELIG LKAKIIRASH 70 80 90 100 110 120 PELVGIEGYV LDETRNTLTI CGERVWVIPK DVVELEFEVG DKRIRINGRE LIGRPEMRLK KRWRR

References

[1]

"The complete genome sequence of Thermococcus onnurineus NA1 reveals a mixed heterotrophic and carboxydotrophic metabolism." Lee H.S., Kang S.G., Bae S.S., Lim J.K., Cho Y., Kim Y.J., Jeon J.H., Cha S.-S., Kwon K.K., Kim H.-T., Park C.-J., Lee H.-W., Kim S.I., Chun J., Colwell R.R., Kim S.-J., Lee J.-H. J. Bacteriol. 190:7491-7499(2008) [PubMed: 18790866] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000855 Genomic DNA. Translation: ACJ15559.1.
RefSeq	YP_002306456.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	7017721.
GenomeReviews	Gene locus TON_1969 in contig CP000855_GR.
KEGG	ton:TON_1969.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	LDETRNT.
Family and domain databases
HAMAP	MF_00754. [Tree]
InterPro	IPR002730. RNase_P/MRP_p29-sub_euk/arc. [Graphical view]
Gene3D	G3DSA:2.30.30.210. RNase_P_Rpp29. 1 hit.
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNP1_THEON

Accession

Primary (citable) accession number: B6YSM2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	January 20, 2009
Last modified:	November 3, 2009
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)