Reviewed, UniProtKB/Swiss-Prot B6YS49 (SYD_AZOPC)

Names and origin

Protein names

Recommended name:
    Aspartyl-tRNA synthetase
    EC=6.1.1.12
Alternative name(s):
    Aspartate--tRNA ligase
      Short name=AspRS

Gene names

Name:	aspS
Ordered Locus Names:	CFPG_758

Organism

Azobacteroides pseudotrichonymphae genomovar. CFP2 [Complete proteome] [HAMAP]

Taxonomic identifier

511995 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Candidatus Azobacteroides

Protein attributes

Sequence length	583 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). HAMAP MF_00044
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aspartyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP aspartate-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 583	583	Aspartyl-tRNA synthetase HAMAP MF_00044		PRO_1000090958

Sequences

	Sequence		Length	Mass (Da)
	B6YS49-1 [UniParc]. Last modified January 20, 2009. Version 1. Checksum: A7B7DAD0E910005C	FASTA	583	67,026
	10 20 30 40 50 60 MYRTNTCGEL RIVNENQEVI LCGWVQKSRR MSGIVFVDLR DRYGITQLIF NKKVNLALYN 70 80 90 100 110 120 KALELGREWV IQIEGKVVKR FNKNSDIPTG DIEIIVSRLR TLNPSEVPPF TIEENTDGGD 130 140 150 160 170 180 DLRMKYRYLD LRRTLIRSNL ELRHQMVFAI RNYLNSHEFM EVETPVLINS TPEGARDFIV 190 200 210 220 230 240 PSRMNMGEFY SLPQSPQLFK QLLMIAGFDR YFQVVKCFRD EDLRTDRQPE FTQVDCEMSF 250 260 270 280 290 300 VEQEDILSIF EGLTKHLFKT IKGLDISGFS RLSYADAIRF YGSDKPDIRF GMQLVEIKDI 310 320 330 340 350 360 TIGRGFDVFD ESEYVGAICA EGCAFYTRKQ LDELTDFVKH PQIGAAGLIY VRYSFDGSLK 370 380 390 400 410 420 SSVDKFYSTV DLQKWIDRVG AKQGDLVLIL YGEKRETQKQ LSRLRLEMGS RLGLRDKKQF 430 440 450 460 470 480 GCLWVIDFPL FEYDNVLNRF FAKHHPFTSP KQEDVCLLET NPEFVRANAF DMVINGIEIG 490 500 510 520 530 540 GGSIRIHNYE LQKKIFALLG FSESYTQSQF GFFVDAFKYG APPHGGIALG LDRFVATFAG 550 560 570 580 LDSIRDCIAF PKNNSGRDTM VGAPSIISRE RLSELNLIVE GWQ

References

[1]

"Genome of an endosymbiont coupling N2 fixation to cellulolysis within RT protist cells in termite gut." Hongoh Y., Sharma V.K., Prakash T., Noda S., Toh H., Taylor T.D., Kudo T., Sakaki Y., Toyoda A., Hattori M., Ohkuma M. Science 322:1108-1109(2008) [PubMed: 19008447] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP010656 Genomic DNA. Translation: BAG84021.1.
RefSeq	YP_002309432.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	7039309.
GenomeReviews	Gene locus CFPG_758 in contig AP010656_GR.
KEGG	aps:CFPG_758.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_00044. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-reg. IPR002312. Asp-tRNA-synth_IIb. IPR020564. Asp-tRNA-synth_IIb_bac-type. IPR004524. Asp-tRNA-synth_IIb_bac/mt. IPR018153. Asp-tRNA-synth_IIb_C_bac/mt. IPR004115. GAD_dom. IPR012340. NA-bd_OB-fold. IPR004365. NA_bd_OB_tRNA-helicase. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit. PTHR22594:SF5. AspS_bac. 1 hit.
Pfam	PF02938. GAD. 1 hit. PF00152. tRNA-synt_2. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
PRINTS	PR01042. TRNASYNTHASP.
TIGRFAMs	TIGR00459. aspS_bact. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYD_AZOPC

Accession

Primary (citable) accession number: B6YS49

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	January 20, 2009
Last modified:	September 22, 2009
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)