B6YS18 (ARGB_AZOPC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetylglutamate kinase
EC=2.7.2.8

Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferase
NAG kinase
Short name=AGK

Gene names

Name:	argB
Ordered Locus Names:	CFPG_727

Organism

Azobacteroides pseudotrichonymphae genomovar. CFP2 [Complete proteome] [HAMAP]

Taxonomic identifier

511995 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Candidatus Azobacteroides

Protein attributes

Sequence length	258 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082_B
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082_B
Subcellular location	Cytoplasm By similarity HAMAP MF_00082_B.
Sequence similarities	Belongs to the acetylglutamate kinase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetylglutamate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 258	258	Acetylglutamate kinase HAMAP MF_00082_B		PRO_1000117115
Regions
	Region	40 – 41	2	Substrate binding By similarity
Sites
	Binding site	62	1	Substrate By similarity
	Binding site	158	1	Substrate By similarity
	Site	8	1	Transition state stabilizer By similarity
	Site	224	1	Transition state stabilizer By similarity

Sequences

	Sequence		Length	Mass (Da)
	B6YS18 [UniParc]. Last modified January 20, 2009. Version 1. Checksum: 2B0ABAC87F542E44	FASTA	258	28,108
	10 20 30 40 50 60 MERLTIVKVG GEIIRIPEVR DSFLKDFSII AGYKILVHGG GSMLTELARN LDIETQMIDG 70 80 90 100 110 120 RRVTTEKILK LAVMVYAGLI NKEIVVGLQA LGVDALGFTG ADSNIICSEK RPIRDSIDYG 130 140 150 160 170 180 LVGDIQEINV QLLNEFLNKG HTPIFAPITH NGGGQLLNTN ADSIAGELAK VLVYDYNVRL 190 200 210 220 230 240 VYCFDKKGVL YDEGDENSFI SVLSYTDFQR YKENGIIGGG MLPKLDSAFN ALSAGVKEVI 250 ITCASNIKHT GSGTHLKL

References

[1]

"Genome of an endosymbiont coupling N2 fixation to cellulolysis within RT protist cells in termite gut." Hongoh Y., Sharma V.K., Prakash T., Noda S., Toh H., Taylor T.D., Kudo T., Sakaki Y., Toyoda A., Hattori M., Ohkuma M. Science 322:1108-1109(2008) [PubMed: 19008447] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP010656 Genomic DNA. Translation: BAG83990.1.
RefSeq	YP_002309401.1. NC_011565.1.
3D structure databases
ProteinModelPortal	B6YS18.
ModBase	Search...
Protein-protein interaction databases
STRING	B6YS18.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7039270.
GenomeReviews	Gene locus CFPG_727 in contig AP010656_GR.
KEGG	aps:CFPG_727.
PATRIC	31963490. VBICanAzo57536_1098.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG497643.
OMA	GGNAMID.
ProtClustDB	CLSK913611.
Family and domain databases
HAMAP	MF_00082_B. ArgB_B. [Tree]
InterPro	IPR004662. AcgluKinase. IPR001048. Asp/Glu/Uridylate_kinase. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KO	K00930.
Pfam	PF00696. AA_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000728. NAGK. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00761. ArgB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARGB_AZOPC

Accession

Primary (citable) accession number: B6YS18

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	January 20, 2009
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program