B6YS11 (DAPF_AZOPC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Diaminopimelate epimerase
Short name=DAP epimerase
EC=5.1.1.7

Gene names

Name:	dapF
Ordered Locus Names:	CFPG_720

Organism

Azobacteroides pseudotrichonymphae genomovar. CFP2 [Complete proteome] [HAMAP]

Taxonomic identifier

511995 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Candidatus Azobacteroides

Protein attributes

Sequence length	275 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197
Subcellular location	Cytoplasm By similarity HAMAP MF_00197.
Sequence similarities	Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Lysine biosynthesis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	diaminopimelate epimerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 275	275	Diaminopimelate epimerase HAMAP MF_00197		PRO_1000124398
Sites
	Active site	71	1	By similarity
	Active site	220	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	B6YS11 [UniParc]. Last modified January 20, 2009. Version 1. Checksum: E6E7FF4BEA1D0FD5	FASTA	275	31,002
	10 20 30 40 50 60 MKFTKMHGAG NDYIYIDCFK EKIDCPEELA IRLSDRHKGI GSDGLVLIMP SDKCSFRMRM 70 80 90 100 110 120 FNSDGSEAQM CGNAIRCVGK YVYDNGYTRK LNITIETLAG VKQLELFPTN DKIRKVKVNM 130 140 150 160 170 180 GKPILLAKDI PVIWEKEKLI YETIDFSSEQ WILTAVSMGN PHVVIFVEKV SRLDVKRIGK 190 200 210 220 230 240 EIEHHPMFPE KINVDFVEIL SLYHAKMRVW ERGSGETQAC GTGACAALVA SVLNGKLNRK 250 260 270 ATISLLGGDL ELEWDEKTEH VFMTGDASLV FIGEF

References

[1]

"Genome of an endosymbiont coupling N2 fixation to cellulolysis within RT protist cells in termite gut." Hongoh Y., Sharma V.K., Prakash T., Noda S., Toh H., Taylor T.D., Kudo T., Sakaki Y., Toyoda A., Hattori M., Ohkuma M. Science 322:1108-1109(2008) [PubMed: 19008447] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP010656 Genomic DNA. Translation: BAG83983.1.
RefSeq	YP_002309394.1. NC_011565.1.
3D structure databases
ProteinModelPortal	B6YS11.
ModBase	Search...
Protein-protein interaction databases
STRING	B6YS11.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7040025.
GenomeReviews	Gene locus CFPG_720 in contig AP010656_GR.
KEGG	aps:CFPG_720.
PATRIC	31963476. VBICanAzo57536_1091.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG399442.
OMA	FMTGPAT.
ProtClustDB	PRK00450.
Family and domain databases
HAMAP	MF_00197. DAP_epimerase. [Tree]
InterPro	IPR018510. DAP_epimerase_AS. IPR001653. DAP_epimerase_DapF. [Graphical view]
KO	K01778.
Pfam	PF01678. DAP_epimerase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00652. DapF. 1 hit.
PROSITE	PS01326. DAP_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DAPF_AZOPC

Accession

Primary (citable) accession number: B6YS11

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	January 20, 2009
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program