B6YRU6 (AROC_AZOPC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Chorismate synthase
EC=4.2.3.5

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	CFPG_655

Organism

Azobacteroides pseudotrichonymphae genomovar. CFP2 [Complete proteome] [HAMAP]

Taxonomic identifier

511995 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Candidatus Azobacteroides

Protein attributes

Sequence length	354 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity. HAMAP MF_00300
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity. HAMAP MF_00300
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 354	354	Chorismate synthase HAMAP MF_00300		PRO_1000115327

Sequences

	Sequence		Length	Mass (Da)
	B6YRU6 [UniParc]. Last modified January 20, 2009. Version 1. Checksum: 3CAE4925225C4C51	FASTA	354	38,696
	10 20 30 40 50 60 MNTFGNIFKL TSFGESHGTA IGGVIDGCPA GIVLDMEFVQ GELDKRRPGQ SELTTSRNES 70 80 90 100 110 120 DKVEFLSGIY EGKTIGTPIG FIVWNNNQHS SDYDSLKNVF RPSHADYTYF QKYRHYDHRG 130 140 150 160 170 180 GGRSSARETI ARVVAGAIAK LILQKKGIKI TAYVSQVGDI CLSKSYIQVD FSNIEKTAVR 190 200 210 220 230 240 CPDLEIAKQM IALIQSVRLR GDTVGGVITC ICHGVPVGLG NPVFGKLSAA LSNAMMSINA 250 260 270 280 290 300 TKGFDYGMGF NGIHRKGSEA NDLYYRNKDG KIVTKSNYSG GIQGGISSGE DIYFRVAFKP 310 320 330 340 350 VATLLQGQLT VDKDGNEIQL EVKGRHDPCV LPRAVPIVES MAAMTILDYY LYNY

References

[1]

"Genome of an endosymbiont coupling N2 fixation to cellulolysis within RT protist cells in termite gut." Hongoh Y., Sharma V.K., Prakash T., Noda S., Toh H., Taylor T.D., Kudo T., Sakaki Y., Toyoda A., Hattori M., Ohkuma M. Science 322:1108-1109(2008) [PubMed: 19008447] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP010656 Genomic DNA. Translation: BAG83918.1.
RefSeq	YP_002309329.1. NC_011565.1.
3D structure databases
ProteinModelPortal	B6YRU6.
ModBase	Search...
Protein-protein interaction databases
STRING	B6YRU6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7039580.
GenomeReviews	Gene locus CFPG_655 in contig AP010656_GR.
KEGG	aps:CFPG_655.
PATRIC	31963238. VBICanAzo57536_0972.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG292336.
OMA	GVQGGIS.
ProtClustDB	PRK05382.
Family and domain databases
HAMAP	MF_00300. Chorismate_synth. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
KO	K01736.
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
SUPFAM	SSF103263. Chorismate_synth. 1 hit.
TIGRFAMs	TIGR00033. AroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_AZOPC

Accession

Primary (citable) accession number: B6YRU6

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	January 20, 2009
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program